Results 301 to 310 of about 51,218 (319)

Recombinant expression of mutants of the Frankenstein disintegrin, RTS-ocellatusin. Evidence for the independent origin of RGD and KTS/RTS disintegrins

Toxicon, 2012
The requirements to transform a short disintegrin of the RGD clade into an RTS disintegrin, were investigated through the generation of recombinant mutants of ocellatusin in which the RGD tripeptide was substituted for RTS in different positions along the integrin-specificity loop.
Raquel, Sanz-Soler, Carolina, Lorente, Beatriz, Company, Libia, Sanz, Paula, Juárez, Alicia, Pérez, Yun, Zhang, Yang, Jin, Runqiang, Chen, Johannes A, Eble, Juan J, Calvete, Gema, Bolás   +11 more
openaire   +3 more sources

Inhibition of neuropathic pain by a potent disintegrin—triflavin

Neuroscience Letters, 2004
Injury to peripheral nerves may result in severe and intractable neuropathic pain. Many efforts have been focused on the elucidation of the mechanisms of neuropathic pain. It was found here that integrin plays an important role in the induction of neuropathic pain and treatment of disintegrin is able to attenuate neuropathic pain. The rats were induced
Hui-Chin Peng, Wen-Mei Fu, Wei-Zen Sun, Qing-Dong Ling, Tur-Fu Huang, Dah-Yuu Lu, Houng-Chi Liou, Tung-Kai Chang   +7 more
openaire   +3 more sources

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Nature, 1997
R. Black, C. Rauch, C. Kozlosky, J. Peschon, J. Slack, M. Wolfson, B. Castner, K. Stocking, P. Reddy, S. Srinivasan, N. Nelson, N. Boiani, K. Schooley, M. Gerhart, Raymond Davis, J. Fitzner, Richard S. Johnson, R. Paxton, C. March, Douglas Pat Cerretti   +19 more
semanticscholar   +1 more source

Reptile Venom Disintegrins

2021
Juan J. Calvete, Anthony J. Saviola
openaire   +2 more sources

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Nature, 1997
M. Moss, S. Jin, M. Milla, W. Burkhart, H. Carter, Wenjing Chen, W. C. Clay, J. Didsbury, D. Hassler, C. Hoffman, T. Kost, M. Lambert, M. Leesnitzer, P. McCauley, G. McGeehan, Justin E. Mitchell, M. Moyer, G. Pahel, W. Rocque, L. Overton, F. Schoenen, T. Seaton, J. Su, J. Warner, D. Willard, J. Becherer   +25 more
semanticscholar   +1 more source

Snake Venom Disintegrins and Disintegrin-Like Domains: Soluble Antagonists and Cellular Ligands of Integrin Receptors

1997
Snake venoms contain a complex mixture of pharmacologically active peptides and proteins which have many biological activities. Venoms of the Elapidae and Hydrophiidae families are neurotoxic, whereas those from Viperidae and Crotalidae species cause death by either intravascular clotting or systemic and local hemorrhage.1 Predominant in the group of ...
openaire   +2 more sources

Neurtalization of snake venom disintegrins and metalloproteases by polyclonal antibodies against disintegrin

Toxicon, 2018
Elda E. Sánchez, Ilse Diego, Montamas Suntravat   +2 more
openaire   +2 more sources

Isolation and characterization of an anti‐leishmanial disintegrin from Cerastes cerastes venom

Journal of biochemical and molecular toxicology, 2018
D. Allane, Habiba Oussedik-Oumehdi, Z. Harrat, M. Sève, F. Laraba-Djebari   +4 more
semanticscholar   +1 more source

New Insights into Disintegrin Metalloproteases

Inflammation Research, 1999
Lori L. Lopresti-Morrow, P. A. McNiff, Kim F. McClure, Peter G. Mitchell, Thomas J. Carty   +4 more
openaire   +2 more sources

Investigation of Vipera Anatolica Venom Disintegrin via Intracellular Uptake with Radiolabeling Study and Cell-Based Electrochemical Biosensing Assay

Applied Biochemistry and Biotechnology, 2018
Ozge Er, Ece Eksin, H. M. Soylu, B. Göçmen, A. Nalbantsoy, F. Yurt, A. Erdem   +6 more
semanticscholar   +1 more source