Results 231 to 240 of about 778,589 (272)

Lumbar Intervertebral Disk Degeneration

Orthopedic Clinics of North America, 2011
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Samartzis, D, Cheung, KMC
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A validated new classification for intervertebral disk degeneration

Khirurgiya. Zhurnal im. N.I. Pirogova, 2022
To develop a new validated classification of intervertebral disc degeneration.A retrospective observational single-center study included medical records of patients with and without degenerative disease of lumbar intervertebral discs. The interval values of apparent diffusion coefficient (ADC) of intervertebral discs were grouped into degeneration ...
I.A. Stepanov, V.A. Beloborodov, V.A. Sorokovikov   +2 more
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Pathology of disk degeneration

2001
The intervertebral disk is a proper intersomatic joint between two vertebrae, allowing pluridirectional movements. The disk, composed of the pulposus and gelatinous nucleus with collagen fibers and contained inside a fibrous ring, changes its morphology during movements of the column. The intervertebral disks are maintained in place by the two anterior
Aldo Fortuna, Luigi Ferrante, Pierpaolo Lunardi   +2 more
openaire   +1 more source

Quantitative synthetic MRI for evaluation of the lumbar intervertebral disk degeneration in patients with chronic low back pain.

European Journal of Radiology, 2020
PURPOSE To verify the feasibility of synthetic MRI in quantitative evaluation of lumbar intervertebral disk (IVD) degeneration, as compared to the conventional CarrPurcell-Meiboom-Gill (CPMG) T2 mapping approach.
Yuwei Jiang, Lu Yu, Xiaojie Luo, Yue Lin, Bei He, Bing Wu, J. Qu, Tao Wu, Wu Pu-Yeh, Chen Zhang, Chun-Mei Li, Min Chen   +11 more
semanticscholar   +1 more source

Genetics of Lumbar Disk Degeneration

2016
The etiology of LBP is complex and involves multiple factors, with disk degeneration of the lumbar spine being a major contributor. This chapter aims to equip readers with a basic understanding of genetics and introduce the principles and findings of genetic studies in lumbar disk degeneration (LDD), following a general framework for genetic studies of
Kenneth M. C. Cheung, Yan Li, Pak Chung Sham, Danny Chan   +3 more
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IMAGING OF LUMBAR INTERVERTEBRAL DISK DEGENERATION AND AGING, EXCLUDING DISK HERNIATIONS

Radiologic Clinics of North America, 2000
With the advent of CT and MR imaging, physicians have been able to complement their clinical diagnosis of the cause of low back pain with a detailed in vivo image of the structure and soft tissues of the spine. At the same time, there has been an increasing realization that information about morphology alone is not enough to make a definitive diagnosis.
J G, Jarvik, R A, Deyo
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Reactive Oxygen Species‐Scavenging Scaffold with Rapamycin for Treatment of Intervertebral Disk Degeneration

Advanced Healthcare Materials, 2019
The chronic inflammatory microenvironment is characterized by the elevated level of reactive oxygen species (ROS). Here, it is hypothesized that developing an ROS‐scavenging scaffold loaded with rapamycin (Rapa@Gel) may offer a new strategy for ...
Jinyu Bai, Ying-Zi Zhang, Qin Fan, Jia-Lu Xu, H. Shan, Xiang Gao, Qingle Ma, L. Sheng, Xin Zheng, Weinan Cheng, Dazhuang Li, Mingchao Zhang, Y. Hao, Liangzhu Feng, Qian Chen, Xiao-Zhong Zhou, Chao Wang   +16 more
semanticscholar   +1 more source

Bu‐Shen‐Huo‐Xue‐Fang modulates nucleus pulposus cell proliferation and extracellular matrix remodeling in intervertebral disk degeneration through miR‐483 regulation of Wnt pathway

Journal of Cellular Biochemistry, 2019
Intervertebral disk degeneration (IDD) has been widely considered as one of the main causes for low back pain, which can cause a severe impact to human health and huge economic burden to worldwide society.
Shaofeng Yang, Ling-Hui Li, Liguo Zhu, Chao Zhang, Zhaoyong Li, Yantao Guo, Y. Nie, Zhenhua Luo   +7 more
semanticscholar   +1 more source

Intervertebral Disk Degeneration and Emerging Biologic Treatments

American Academy of Orthopaedic Surgeon, 2011
Although understanding of the biologic basis of intervertebral disk (IVD) degeneration is rapidly advancing, the unique IVD environment presents challenges to the development and delivery of biologic treatments. Acceleration of cellular senescence and apoptosis in degenerative IVDs and the depletion of matrix proteins have prompted the development of ...
Christopher K, Kepler, D Greg, Anderson, Chadi, Tannoury, Ravi K, Ponnappan   +3 more
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Classification of Intervertebral Disk Degeneration with Axial T2 Mapping

American Journal of Roentgenology, 2007
The aim of this study was to establish an MRI classification system for intervertebral disks using axial T2 mapping, with a special focus on evaluating early degenerative intervertebral disks.Twenty-nine healthy volunteers (19 men, 10 women; age range, 20-44 years; mean age, 31.8 years) were studied, and axial T2 mapping was performed for the L3-L4, L4-
Watanabe, Atsuya, Benneker, Lorin Michael, Boesch, Christoph Hans, Watanabe, Tomoko, Obata, Takayuki, Anderson, Suzanne E   +5 more
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