Results 41 to 50 of about 778,589 (272)

The molecular basis of intervertebral disk degeneration

open access: yesOrthopedic Clinics of North America, 2003
At present, the molecular evidence involved in the degeneration of the IVD is still in its primitive stage. In general, however, intrinsic, extrinsic, and generic factors all have shown a contribution to the initiation of degeneration. These factors may stimulate cytokines and directly or indirectly generate the cellular events thus far detected and ...
Chung, S.A., Khan, S.N., Diwan, Ashish
openaire   +4 more sources

The Association of Intervertebral Disk Degeneration on MRI and Low Back Pain: A Population-Based Study

open access: yesGlobal Spine Journal, 2012
Introduction According to previous studies, the presence of disk degeneration based on MRI and its association with low back pain (LBP) remains questionable.
D. Samartzis   +3 more
doaj   +1 more source

Chronic Unpredictable Stress Induces Intervertebral Disk Cell Apoptosis and Degeneration

open access: yesGlobal Spine Journal, 2012
Introduction Animal model was used to study the effects of chronic unpredictable stress (CUS) on the intervertebral disk (IVD). Stress is a predictor for low back disability in persons with earlier low back pain (LBP) and LBP is most common in the early ...
H. Reihani Kermani   +3 more
doaj   +1 more source

Current Progress in the Endogenous Repair of Intervertebral Disk Degeneration Based on Progenitor Cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Intervertebral disk (IVD) degeneration is one of the most common musculoskeletal disease. Current clinical treatment paradigms for IVD degeneration cannot completely restore the structural and biomechanical functions of the IVD.
Yan-Bin Zhang   +6 more
semanticscholar   +1 more source

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)

open access: yesExperimental and Therapeutic Medicine, 2021
Intervertebral disc degeneration (IVDD) is a degenerative musculoskeletal disorder with multiple causative factors, such as age, genetics, mechanics and life style.
Jian Jiang   +4 more
semanticscholar   +1 more source

Correlation between MMP-3 Activity and Intervertebral Disk Degeneration According to Radiologic Data

open access: yesGlobal Spine Journal, 2012
Introduction During the degeneration process, tissue resorption causes a progressive and important decrease in intervertebral disk height. The main characteristics of disk degeneration are intradiscal clefts and teardrops.
S. Canbay, S. caglar, N. turhan, K. Arda
doaj   +1 more source

Evaluating the Impact of Mechanical Manipulation on Inducing Disk Degeneration: A 3-Month Radiologic Follow-Up of Intervertebral Disk Degeneration in a Needle-Punctured Rat Tail Model

open access: yesGlobal Spine Journal, 2012
Introduction The rat tail model for the intervertebral disk degeneration has recently been receiving a high level of interest among the intervertebral disk degeneration studies.
R. Härtl   +6 more
doaj   +1 more source

Effect of Spino-Pelvic Sagittal Balance on Degree of Disk Degeneration in the Lumbar Spine

open access: yesGlobal Spine Journal, 2012
Introduction Recent studies have focused on spino-pelvic sagittal balance. Changes in sagittal balance could alter the load on the spine and may affect spinal mobility.
Z. Zheng   +5 more
doaj   +1 more source

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

open access: yesMolecular Therapy: Nucleic Acids, 2019
Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans.
Chin-Yu Lin   +5 more
doaj   +1 more source

Intervertebral Disk Degeneration in Rabbits: Histomorphometric and Histomorphological Effects of Aloe Vera Gel

open access: yesGlobal Spine Journal, 2021
Study Design: This is an experimental study using an animal model. Objectives: Disk degeneration is a common cause of low back pain. However, few attempts have been made to proffer a medical solution.
Busuyi Kolade Akinola MBChB, MSc (Anatomy)   +1 more
doaj   +1 more source

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