Results 31 to 40 of about 386,467 (345)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Silicon p-i-n Mesa-Photodiode Technology

open access: yesEast European Journal of Physics
The paper proposes the technology of silicon p-i-n mesa-photodiodes, which allows to exclude one high-temperature operation from the technological route.
Mykola S. Kukurudziak   +2 more
doaj   +1 more source

The study of plastic deformation in the crack surrounding in AZ61 alloy [PDF]

open access: yesFME Transactions, 2013
This paper deals with the study of effect of microstructure on the development of plastic deformation around the propagating cracks of the magnesium alloy whose corrosion resistance is increased by the addition of 0.5 wt. % Ca.
Palček P.   +2 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Dislocation Behavior in TiVTa Multi-Principal Element Alloys: A Nanoindentation Simulation Study

open access: yesCrystals
Molecular dynamics simulations of nanoindentation were conducted to compare the dislocation behavior in a pure V and a TiVTa multi-principal element alloy (MPEA) with [100] and [111] crystal orientations.
Shumin Wang   +4 more
doaj   +1 more source

Rocking Curve Imaging Investigation of the Long-Range Distortion Field between Parallel Dislocations with Opposite Burgers Vectors

open access: yesApplied Sciences, 2021
We observe a long-range distortion field between parallel dislocations with opposite Burgers vectors in a platelet-shaped single crystal of 4H-SiC with a low dislocation density (~103 cm/cm3).
Thu Nhi Tran Caliste   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

A bcc refractory high-entropy alloy: the ideal case of smooth plastic flow

open access: yesMaterials Research Letters
Single crystalline metals exhibit correlated dislocation dynamics, irrespective of lattice system. This collective evolution of dislocation structures is intermittent and scale-free, implying divergent length scales that play a critical role in failure ...
Yen-Ting Chang   +4 more
doaj   +1 more source

An investigation on the precipitates in T5 treated high vacuum die-casting AE44–2 magnesium alloy

open access: yesMaterials Research Express, 2022
The AE44-2 magnesium alloy was fabricated via die-casting under high vacuum (denoted as HVDC-AE44-2 alloy). The microstructures and mechanical properties of the aged HVDC-AE44-2 alloys were investigated.
Yongfeng Li   +6 more
doaj   +1 more source

Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study

open access: yesBMJ Open, 2017
Objective This cohort study evaluates the unknown age-specific and gender-specific incidence of primary shoulder dislocations in the UK. Setting UK primary care data from the Clinical Practice Research Datalink (CPRD) were used to identify patients aged ...
Anjali Shah   +13 more
semanticscholar   +1 more source

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