Results 1 to 10 of about 5,552,271 (346)

Development and Validation of a New Substance Use Disorder Screening Test Based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)

Journal of Health Science and Medical Research, 2023
Objective: The lack of a screening tool for substance use disorders is a significant problem for health care workers for patient care and referral.
Sukuma Saengduenchai, S. Nilaban, Tanya Singtho, Apichart Ranuwattananon, R. Kalayasiri   +4 more
semanticscholar   +1 more source

Eye movement patterns correlate with overt emotional behaviours in rapid eye movement sleep

Scientific Reports, 2022
Growing evidence suggests that sleep plays a key role in regulating emotions. Rapid eye movements (REMs) in REM sleep could be associated with dreams emotions, but supporting evidence is indirect.
Jean-Baptiste Maranci, Milan Nigam, Luc Masset, Eva-Flore Msika, Marie Charlotte Vionnet, Charlotte Chaumereil, Marie Vidailhet, Smaranda Leu-Semenescu, Isabelle Arnulf   +8 more
doaj   +1 more source

Which Groups of Children Are at More Risk of Fatality during COVID-19 Pandemic? A Case-Control Study in Yazd, Iran

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
Introduction. The study aims to investigate the characteristics, comorbidities, laboratory findings, and clinical manifestations of under 18-year-old patients who died with the diagnosis of COVID-19 and determination of the most prevalent risk factors ...
Behnam Shafaei, Zahra Nafei, Mehran Karimi, Nasrin Behniafard, Farimah Shamsi, Masoud Faisal, Amir Pasha Amel Shahbaz, Elahe Akbarian   +7 more
doaj   +1 more source

M2-AChR Mediates Rapid Antidepressant Effects of Scopolamine Through Activating the mTORC1-BDNF Signaling Pathway in the Medial Prefrontal Cortex

Frontiers in Psychiatry, 2021
Background: Scopolamine, a non-selective muscarinic acetylcholine receptor (M1~5-AChR) antagonist, has rapid and robust antidepressant effects in humans and other species. However, which of the five M-AChRs mediates these therapeutic effects has not been
Shuang Liu, Dandan Shi, Zuoli Sun, Yi He, Jian Yang, Jian Yang, Gang Wang, Gang Wang   +7 more
doaj   +1 more source

Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
Introduction. COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. Materials and Methods.
Farimah Shamsi, Mehran Karimi, Zahra Nafei, Elahe Akbarian   +3 more
doaj   +1 more source

Medical Cannabis for Gilles de la Tourette Syndrome: An Open-Label Prospective Study

Behavioural Neurology, 2022
Objectives. Assessing the effectiveness and tolerability of medical cannabis (MC) treatment on Gilles de la Tourette syndrome (GTS) patients. Methods. We report on an open-label, prospective study on the effect of MC on adult GTS patients. MC mode of use
Saar Anis, Corinne Zalomek, Amos D. Korczyn, Alina Rosenberg, Nir Giladi, Tanya Gurevich   +5 more
doaj   +1 more source

Slow wave activity across sleep-night could predict levodopa-induced dyskinesia

Scientific Reports, 2023
A disruption in the slow wave activity (SWA) mediated synaptic downscaling process features Parkinson's disease (PD) patients presenting levodopa-induced dyskinesia (LID).
Ninfa Amato, Serena Caverzasio, Mauro Manconi, Claudio Staedler, Alain Kaelin-Lang, Salvatore Galati   +5 more
doaj   +1 more source

A novel outpatient treatment model for patients with severe and enduring anorexia nervosa: an observational study of patient characteristics, treatment goals, and treatment course

Journal of Eating Disorders, 2023
Background Approximately 20–30% of people with anorexia nervosa develop an enduring form of the disorder. In the present study a newly developed outpatient treatment unit for patients with severe and enduring anorexia nervosa was described. The treatment
Monica Ålgars, Svetlana Oshukova, Jaana Suokas   +2 more
doaj   +1 more source

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

Nature Genetics, 2021
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci.
N. Mullins, A. Forstner, K. O’Connell, B. Coombes, J. Coleman, Zhen Qiao, T. Als, T. Bigdeli, S. Børte, J. Bryois, A. Charney, O. K. Drange, M. Gandal, S. Hagenaars, M. Ikeda, Nolan Kamitaki, Minsoo Kim, Kristi Krebs, Georgia Panagiotaropoulou, B. Schilder, Laura G. Sloofman, S. Steinberg, V. Trubetskoy, B. Winsvold, H. Won, L. Abramova, K. Adorjan, E. Agerbo, M. A. Al Eissa, D. Albani, N. Alliey-Rodriguez, A. Anjorin, V. Antilla, A. Antoniou, S. Awasthi, J. Baek, Marie Bækvad-Hansen, N. Bass, M. Bauer, E. Beins, Sarah E. Bergen, A. Birner, C. Bøcker Pedersen, E. Bøen, M. Boks, R. Bosch, M. Brum, B. Brumpton, N. Brunkhorst-Kanaan, M. Budde, J. Bybjerg-Grauholm, W. Byerley, M. Cairns, M. Casas, P. Cervantes, Toni‐Kim Clarke, C. Cruceanu, A. Cuellar-Barboza, J. Cunningham, D. Curtis, P. Czerski, A. Dale, N. Dalkner, F. David, F. Degenhardt, S. Djurovic, Amanda Dobbyn, A. Douzenis, T. Elvsåshagen, V. Escott-Price, I. Ferrier, A. Fiorentino, T. Foroud, L. Forty, J. Frank, O. Frei, N. Freimer, L. Frisén, K. Gade, J. Garnham, J. Gelernter, Marianne Giørtz Pedersen, I. Gizer, S. Gordon, K. Gordon-Smith, T. Greenwood, J. Grove, J. Guzmán-Parra, Kyooseob Ha, M. Haraldsson, M. Hautzinger, U. Heilbronner, D. Hellgren, S. Herms, P. Hoffmann, P. Holmans, L. Huckins, S. Jamain, Jessica S. Johnson, J. Kalman, Y. Kamatani, J. Kennedy, S. Kittel-Schneider, J. Knowles, M. Kogevinas, M. Koromina, T. Kranz, H. Kranzler, M. Kubo, R. Kupka, S. Kushner, C. Lavebratt, J. Lawrence, M. Leber, Heon-Jeong Lee, Phil H. Lee, S. Levy, Catrin E Lewis, C. Liao, S. Lucae, M. Lundberg, D. Macintyre, S. Magnusson, W. Maier, A. Maihofer, D. Malaspina, E. Maratou, Lina Martinsson, M. Mattheisen, S. Mccarroll, N. McGregor, P. McGuffin, J. Mckay, H. Medeiros, S. Medland, V. Millischer, G. Montgomery, J. Moran, D. Morris, Thomas W. Mühleisen, N. O’Brien, C. O’Donovan, Loes M. Olde Loohuis, L. Oruč, S. Papiol, A. Pardiñas, A. Perry, A. Pfennig, E. Porichi, J. Potash, D. Quested, T. Raj, M. Rapaport, J. R. DePaulo, E. J. Regeer, J. Rice, F. Rivas, M. Rivera, Julian Roth, P. Roussos, D. Ruderfer, C. Sánchez-Mora, E. Schulte, F. Senner, S. Sharp, P. Shilling, E. Sigurdsson, L. Sirignano, C. Slaney, O. Smeland, Danny J. Smith, J. Sobell, Christine Søholm Hansen, M. Soler Artigas, A. Spijker, Dan J Stein, J. Strauss, B. Świątkowska, C. Terao, T. Thorgeirsson, Claudio Toma, P. Tooney, Evangelia Eirini Tsermpini, M. Vawter, H. Vedder, J. Walters, S. Witt, S. Xi, Wei Xu, J. Yang, A. Young, Hannah Young, P. Zandi, Hang Zhou, Lea Zillich, R. Adolfsson, I. Agartz, M. Alda, L. Alfredsson, Gulja Babadjanova, L. Backlund, B. Baune, F. Bellivier, S. Bengesser, W. Berrettini, D. Blackwood, M. Boehnke, A. Børglum, G. Breen, V. Carr, S. Catts, A. Corvin, N. Craddock, U. Dannlowski, D. Dikeos, T. Esko, B. Étain, P. Ferentinos, M. Frye, J. Fullerton, M. Gawlik, E. Gershon, F. Goes, Melissa J. Green, M. Grigoroiu-Serbanescu, J. Hauser, F. Henskens, J. Hillert, K. Hong, D. Hougaard, C. Hultman, K. Hveem, N. Iwata, A. Jablensky, I. Jones, L. Jones, R. Kahn, J. Kelsoe, G. Kirov, M. Landén, M. Leboyer, C. Lewis, Qingqin S. Li, J. Lissowska, C. Lochner, C. Loughland, N. Martin, C. Mathews, F. Mayoral, S. McElroy, A. McIntosh, F. McMahon, I. Melle, P. Michie, L. Milani, P. Mitchell, G. Morken, O. Mors, P. Mortensen, B. Mowry, B. Müller-Myhsok, R. Myers, B. Neale, C. Nievergelt, M. Nordentoft, M. Nöthen, M. O’Donovan, K. Oedegaard, T. Olsson, M. Owen, S. Paciga, C. Pantelis, C. Pato, M. Pato, G. Patrinos, R. Perlis, D. Posthuma, J. Ramos-Quiroga, A. Reif, E. Reininghaus, M. Ribasés, M. Rietschel, S. Ripke, G. Rouleau, Takeo Saito, U. Schall, M. Schalling, P. Schofield, T. Schulze, L. Scott, R. Scott, A. Serretti, C. Shannon Weickert, J. Smoller, H. Stefánsson, K. Stefánsson, E. Stordal, F. Streit, P. Sullivan, G. Turecki, A. Vaaler, E. Vieta, J. Vincent, I. Waldman, T. Weickert, T. Werge, N. Wray, J. Zwart, J. Biernacka, J. Nurnberger, S. Cichon, H. Edenberg, E. Stahl, A. McQuillin, A. Di Florio, R. Ophoff, O. Andreassen   +316 more
semanticscholar   +1 more source

Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder

Frontiers in Psychiatry, 2023
BackgroundWe aimed to explore the predictive role of serum BDNF and anxiety-related variables in changes in somatic symptoms post-escitalopram treatment in panic disorder (PD) patients.MethodsNinety PD patients and 99 healthy controls (HCs) were enrolled.
Jiaxin Li, Ru Li, Dazhi Li, Jian Zhang, Xingguang Luo, Yong Zhang   +5 more
doaj   +1 more source