Results 101 to 110 of about 222,328 (285)

Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods

open access: yesPharmaceutics, 2019
The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray ...
Tereza Školáková   +5 more
doaj   +1 more source

What Explains Growth and Inflation Dispersions in EMU? [PDF]

open access: yes
This paper’s analysis of growth and inflation dispersions in the euro area reveals several findings. First, these dispersions have declined appreciably since EMU.
Emil Stavrev
core  

Weak Gravitational Lensing by a Sample of X-Ray Luminous Clusters of Galaxies -- II. Comparison with Virial Masses

open access: yes, 2002
Dynamic velocity dispersion and mass estimates are given for a sample of five X-ray luminous rich clusters of galaxies at intermediate redshifts (z~0.3) drawn from a sample of 39 clusters for which we have obtained gravitational lens mass estimates.
Adami C.   +14 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Synthesis of Water-Based Dispersions of Polymer/TiO2 Hybrid Nanospheres

open access: yesNanomaterials, 2015
We develop a strategy for preparing water-based dispersions of polymer/TiO2 nanospheres that can be used to form composite materials applicable in various fields. The formed hybrid nanospheres are monodisperse and possess a hierarchical structure.
Lu Jin, Hua Wu, Massimo Morbidelli
doaj   +1 more source

Estimating the baryonic masses of face-on spiral galaxies from stellar kinematics

open access: yes, 2017
The kinematic dispersions of disc stars can be used to measure the dynamic contributions of baryons to the rotation curves of spiral galaxies and hence to trace the amount and distribution of the remaining dark matter.
Hessman, Frederic V.
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Amorphous Solid Dispersions: Implication of Method of Preparation and Physicochemical Properties of API and Excipients

open access: yesPharmaceutics
The present study investigated the effect of different polymers and manufacturing methods (hot melt extrusion, HME, and spray drying, SD) on the solid state, stability and pharmaceutical performance of amorphous solid dispersions.
Varun Kushwah   +3 more
doaj   +1 more source

Improved dissolution of Kaempferia parviflora extract for oral administration by preparing solid dispersion via solvent evaporation

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Kaempferia parviflora, a plant in the family Zingiberaceae, has been used in Thai traditional medicines for treating hypertension and promoting longevity with good health and well-being.
Yotsanan Weerapol   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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