Results 111 to 120 of about 222,783 (286)
PharmaceuticsThe present study investigated the effect of different polymers and manufacturing methods (hot melt extrusion, HME, and spray drying, SD) on the solid state, stability and pharmaceutical performance of amorphous solid dispersions.
Varun Kushwah +3 more
doaj +1 more source
Pharmaceutics, 2019 In this study, supercritical fluid (SCF) technology was applied to prepare reliable solid dispersions of pharmaceutical compounds with limited bioavailability using ibuprofen (IBU) as a model compound.
Fei Han +6 more
doaj +1 more source
Orbital Dependence of Quasiparticle Lifetimes in Sr2RuO4
, 2006 Using a phenomenological Hamiltonian, we investigate the quasiparticle lifetimes and dispersions in the three low energy bands, gamma, beta, and alpha of Sr2RuO4.
C. Honerkamp, R. M. Konik, T. M. Rice
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Asian Journal of Pharmaceutical Sciences, 2017 Kaempferia parviflora, a plant in the family Zingiberaceae, has been used in Thai traditional medicines for treating hypertension and promoting longevity with good health and well-being.
Yotsanan Weerapol +3 more
doaj +1 more source
Oscillations of Bose condensates in a one-dimensional optical superlattice
, 2005 Oscillations of atomic Bose-Einstein condensates in a 1D optical lattice with a two-point basis is investigated. In the low-frequency regime, four branches of modes are resolved, that correspond to the transverse in-phase and out-of-phase breathing modes,
Huang, C. C., Wu, W. C.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
APPLICATION OF SOLID DISPERSIONS WITH NON STEROIDAL ANTI INFLAMMATORY DRUGS IN PHARMACY
Разработка и регистрация лекарственных средств, 2019 The article provides a brief overview of the use of solid dispersions of NSAIDs with polymeric carriers. Solid dispersions are entered in various dosage forms for different purposes.
I. I. Krasnuk (Junior) +8 more
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