Results 101 to 110 of about 2,289,456 (329)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The effect of the spacing of background elements upon optomotor memory responses in the crab: the influence of adding or deleting features during darkness [PDF]
, 1977 1. Study was made of the effect of separation between stripes in the visual field upon responses which indicate memory of those stripes. 2. The amount of separation between white stripes had very little effect, whereas response strength and the amount of
Hirsh, Richard, Wiersma, C. A. G.
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Crisis and displacement in Somalia [PDF]
, 2009 Can displacement shocks offer opportunities to change theparameters of response to protracted refugee ...
Lindley, Anna
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Multi-dimensional migration challenges in North Africa [PDF]
Forced Migration Review, 2007 Facing tighter European border controls, increasing numbers of refugees and asylum seekers from sub-Saharan countries find themselves stranded in North Africa.
Johannes van der Klaauw
doaj
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Portable fiber optic coupled Doppler interferometer system for detonation and shock wave diagnostics [PDF]
, 1993 Testing and analysis of shock wave characteristics such as detonators and ground shock propagation frequently require a method of measuring velocity and displacement of the surface of interest. One method of measurement is Doppler interferometry.
Fleming, Kevin J.
core +1 more source
Breakage and displacement of the high-speed hand-piece bur during impacted mandibular third molar extraction: three cases [PDF]
, 2022 Kuncai Li +3 more
openalex +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source