Results 111 to 120 of about 2,289,456 (329)
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Peacebuilding in displacement [PDF]
Despite their knowledge and experience, and their vestedinterest in resolving conflicts in their countries, refugees arenot yet being fully engaged as peace advocates.
Tammi Sharpe, Silvio Cordova
doaj
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The aesthetics of displacement in Farouk Juwaida's poetry
Rasha AlAbsi
openalex +2 more sources
Performance Evaluation and Oil Displacement Effect of Amphiphilic Polymer Heavy Oil Activator [PDF]
Jiqiang Zhi +6 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Invisibility of urban IDPs in Europe [PDF]
Some IDPs in the Balkans, Caucasus and Turkey seek ‘invisibility’for security reasons. Others become invisible when they are forcedto move again within the city by the actions of city authorities orproperty owners.
Marzia Montemurro, Nadine Walicki
doaj
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Learning away from home: the BEFARe project [PDF]
BEFARe – Basic Education For Afghan Refugees– administers the world’s largest and longest-runningemergency education project for refugees.
Shakir Ishaq, Atle Hetland
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

