Results 231 to 240 of about 1,230,257 (264)
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2012
Personalized medicine requires knowledge of factors influencing disease susceptibility and progression as well as effective treatments which minimize adverse drug reactions (ADRs). Surprisingly little attention has focused on the impact of sex on clinical therapeutics.
Amy C.M. Mattison Faye +1 more
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Personalized medicine requires knowledge of factors influencing disease susceptibility and progression as well as effective treatments which minimize adverse drug reactions (ADRs). Surprisingly little attention has focused on the impact of sex on clinical therapeutics.
Amy C.M. Mattison Faye +1 more
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Effect of phenobarbital on theophylline disposition
Journal of Allergy and Clinical Immunology, 1978The effect of chronic phenobarbital administration on the pharmacokinetics of theophylline was studied in 6 healthy, nonsmoking adults. Subject compliance was verified by the determination of plasma phenobarbital levels. Following four weeks of phenobarbital administration, all six subjects showed a resultant increase in serum clearance varying from 11%
John C. Taylor +5 more
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Prospect Theory and the Disposition Effect
Journal of Financial and Quantitative Analysis, 2010AbstractThis paper shows that prospect theory is unlikely to explain the disposition effect. Prospect theory predicts that the propensity to sell a stock declines as its price moves away from the purchase price in either direction. Trading data, on the other hand, show that the propensity to sell jumps at zero return, but it is approximately constant ...
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Effect of Ranitidine on Chloroquine Disposition
Drug Intelligence & Clinical Pharmacy, 1987Ten healthy, male volunteers (aged 19–27 yr; weight 62–67 kg) were randomly distributed into control and test groups of five subjects each in a controlled study on the effect of ranitidine on chloroquine disposition. The control group subjects received two tablets of chloroquine sulfate (300-mg base) only.
E. E. Essien, Ette Ei, Brown-Awala A
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The Effect of Probenecid on Nafcillin Disposition
The Journal of Clinical Pharmacology, 1982Abstract: Five normal male volunteers participated in an open crossover study designed to examine the disposition of nafcillin given intravenously with and without probenecid. Each subject received two 500 mg iv doses of sodium nafcillin seven days apart, one dose without probenecid and another dose during oral probenecid administration of 1.0 Gm at ...
Gerald J. Yakatan +2 more
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Effect of pentobarbital on the disposition of alprenolol
Clinical Pharmacology & Therapeutics, 1977Alprenolol was administered orally and intravenously to 5 healthy subjects before and after IO to 14 daily doses of 0.1 gm pentobarbital. The area under the plasma concentration time curve after an oral 200‐mg dose decreased from 706 ± 277 to 154 ± 48 ng/ml .
Gunnar Alván +3 more
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Effect of quinolones on caffeine disposition
Clinical Pharmacology and Therapeutics, 1989Six healthy volunteers received a single caffeine dose after pretreatment with norfloxacin, pipemidic acid, or placebo in a crossover, randomized, single-blind clinical trial. Quinolones altered the pharmacokinetics of caffeine, with a significant increase in the AUCs and a decrease in plasma clearance. The elimination half-life increased significantly
Marcelli Carbó +4 more
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The disposition effect: a survey
Management Review Quarterly, 2017The disposition effect is a well-recognized behavioral economic phenomenon which has been studied in numerous papers during the last three decades. Besides a literature review of the major theoretical, empirical, and experimental papers, the body of academic literature is subjected to a bibliometric analysis where all papers are taken into account ...
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Effect of route of administration on drug disposition
Journal of Pharmacokinetics and Biopharmaceutics, 1972An increasing body of information tends to support the hypothesis that drug effect, therapeutic or toxic, is more closely correlated with plasma concentration than dose (Levy, 1968). Absorption is one important determinant of drug plasma levels. Distribution and elimination are others.
Malcolm Rowland, Sidney Riegelman
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The Disposition Effect and the Takeover Market
SSRN Electronic Journal, 2009Many investors exhibit the disposition effect when they trade. They tend to hold losing stocks too long but sell winning stocks too soon. In this paper, I investigate whether and how this trading bias affects the takeover market. I posit that if a large subset of investors is prone to the disposition effect, once their stocks become the acquisition ...
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