Results 1 to 10 of about 43,835 (279)

Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary. [PDF]

Neurol Ther, 2023
Narcolepsy is associated with disrupted nighttime sleep (DNS). Sodium oxybate (SXB; Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and excessive daytime sleepiness in patients 7 years or older with narcolepsy.
Rosenberg R, Braceras R, Macfadden W, Candler S, Black J, Ruoff C.   +5 more
europepmc   +7 more sources

Disrupted nighttime sleep and sleep instability in narcolepsy. [PDF]

J Clin Sleep Med, 2022
This review aimed to summarize current knowledge about disrupted nighttime sleep (DNS) and sleep instability in narcolepsy, including self-reported and objective assessments, potential causes of sleep instability, health consequences and functional ...
Maski K, Mignot E, Plazzi G, Dauvilliers Y.   +3 more
europepmc   +7 more sources

Letter to the Editor regarding: "Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary" by R. Rosenberg et al. [PDF]

Neurol Ther
Roth T.
europepmc   +7 more sources

Once-nightly sodium oxybate (FT218) improved symptoms of disrupted nighttime sleep in people with narcolepsy: a plain language summary. [PDF]

J Comp Eff Res, 2023
What is this summary about? This is a plain language summary of a published article in the journal CNS Drugs. Narcolepsy is a rare sleep condition.
Roth T, Thorpy MJ, Kushida CA, Horsnell M, Gudeman J.   +4 more
europepmc   +5 more sources

Defining disrupted nighttime sleep and assessing its diagnostic utility for pediatric narcolepsy type 1. [PDF]

Sleep, 2020
STUDY OBJECTIVES Disrupted nighttime sleep (DNS) is a core narcolepsy symptom of unconsolidated sleep resulting from hypocretin neuron loss. In this study, we define a DNS objective measure and evaluate its diagnostic utility for pediatric narcolepsy ...
Maski K, Pizza F, Liu S, Steinhart E, Little E, Colclasure A, Diniz Behn C, Vandi S, Antelmi E, Weller E, Scammell TE, Plazzi G.   +11 more
europepmc   +7 more sources

Disrupted nighttime sleep in narcolepsy. [PDF]

J Clin Sleep Med, 2013
Characterize disrupted nighttime sleep (DNS) in narcolepsy, an important symptom of narcolepsy.A panel of international narcolepsy experts was convened in 2011 to build a consensus characterization of DNS in patients with narcolepsy. A literature search of the Medline (1965 to date), Medline In-Process (latest weeks), Embase (1974 to date), Embase ...
Roth T, Dauvilliers Y, Mignot E, Montplaisir J, Paul J, Swick T, Zee P.   +6 more
europepmc   +7 more sources

Effect of FT218, a Once-Nightly Sodium Oxybate Formulation, on Disrupted Nighttime Sleep in Patients with Narcolepsy: Results from the Randomized Phase III REST-ON Trial. [PDF]

CNS Drugs, 2022
Sodium oxybate has been recognized as a gold standard for the treatment of disrupted nighttime sleep due to narcolepsy. Its short half-life and immediate-release formulation require patients to awaken 2.5–4 h after their bedtime dose to take a second ...
Roth T, Dauvilliers Y, Thorpy MJ, Kushida C, Corser BC, Bogan R, Rosenberg R, Dubow J, Seiden D.   +8 more
europepmc   +6 more sources

Improvements in daytime sleepiness and disrupted nighttime sleep with once-nightly sodium oxybate in people with narcolepsy type 1 and type 2: a plain language summary. [PDF]

J Comp Eff Res
What is this summary about? This is a plain language summary of a published article in the journal Sleep. Narcolepsy is a sleep condition that has 2 different subtypes: narcolepsy type 1 and narcolepsy type 2. These are called NT1 and NT2 for short.
Dauvilliers Y, Roth T, Bogan R, Thorpy MJ, Morse AM, Ascencion F, Gudeman J.   +6 more
europepmc   +5 more sources

Characterizing disrupted nighttime sleep and associated functional outcomes in youth with narcolepsy type 1. [PDF]

J Clin Sleep Med
Disrupted nighttime sleep and sleep instability are common in children and adolescents with narcolepsy type 1, but optimal objective sleep measures have not been determined. We compared self-reported and objective sleep measures between young people with
Heckler G, Worhach J, Wang G, Szilagyi K, Zhang B, Behn CD, Scammell T, Maski K.   +7 more
europepmc   +4 more sources

Correction: Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary. [PDF]

Neurol Ther
Rosenberg R, Braceras R, Macfadden W, Candler S, Black J, Ruoff C.   +5 more
europepmc   +3 more sources