Response to Letter to the Editor Regarding "Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients With Narcolepsy: A Commentary". [PDF]
Ruoff C, Candler S, Black J.
europepmc +6 more sources
STUDY OBJECTIVES Despite its high frequency in narcolepsy type 1(NT1), disrupted nocturnal sleep (DNS) remains understudied, and its determinants have been poorly assessed.
L. Barateau +7 more
semanticscholar +5 more sources
OBJECTIVE To assess the effects of three narcolepsy treatment modalities on sleep stage shifts associated with disrupted nighttime sleep (DNS) using data from a clinical trial.
Y. Dauvilliers +5 more
semanticscholar +5 more sources
Objective sleep quality of healthy older men and women is differentially disrupted by nighttime periodic blood sampling via indwelling catheter. [PDF]
Elucidation of sleep-endocrine relationships requires frequent blood sampling during sleep recording. Unfortunately, such sampling can itself affect sleep and indirectly, hormonal patterns. We examined the effect of catheterization and frequent nighttime
M. Vitiello +5 more
semanticscholar +5 more sources
Effects of oxybate dose and regimen on disrupted nighttime sleep and sleep architecture.
Many components of sleep are disrupted in patients with narcolepsy, including sleep quality, sleep architecture, and sleep stability (ie, frequent awakenings/arousals and frequent shifts from deeper to lighter stages of sleep).
Thomas Roth +4 more
semanticscholar +3 more sources
0941 Defining Disrupted Nighttime Sleep in Pediatric Narcolepsy [PDF]
Disrupted nighttime sleep (DNS) is a core narcolepsy symptom subjectively described as spontaneous awakenings during the night, but researchers use varied polysomnogram (PSG) definitions based on sleep state transitions, NREM 1% and poor sleep ...
K. Maski +9 more
semanticscholar +2 more sources
Effect of sodium oxybate on disrupted nighttime sleep in patients with narcolepsy [PDF]
This post hoc analysis evaluated the dose‐related effects of sodium oxybate on sleep continuity and nocturnal sleep quality in patients with narcolepsy–cataplexy.
T. Roth +5 more
semanticscholar +3 more sources
Study on the sleep-wake circadian rhythm and phenotypic characteristics in the acute phase of hemorrhagic stroke. [PDF]
ObjectiveTo investigate the sleep–wake circadian rhythm and phenotypic characteristics in patients with acute intracerebral hemorrhage (ICH), and to explore the relationship and potential mechanisms between sleep–wake phenotypes and circadian rhythm ...
Yuan X +9 more
europepmc +2 more sources
In people with NT1, Disrupted Nighttime sleep (DNS) can be measured using the Wake/N1 Index, the number of transitions from sleep to wake or N1 sleep per hour of sleep.
G. Heckler +3 more
semanticscholar +2 more sources
646 The Impact of the COVID-19 Pandemic on Nighttime Room Entries and Sleep Disruptions for Pediatric Patients [PDF]
Introduction Sleep is critical to children’s health and recovery, but pediatric inpatient sleep is often disrupted by nonessential overnight interruptions.
J. Riehm +9 more
semanticscholar +2 more sources

