Results 111 to 120 of about 2,396,820 (308)
When Harry left Sally: A New Estimate of Marital Disruption in the U.S., 1860 - 1948 [PDF]
Divorce rate is a poor indicator of marital instability because many marital disruptions never become divorces. This paper provides the first estimate of the rate of marital disruption in the U.S. in 1860 - 1948.
Tomas Cvrcek
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Disrupt and unlock? The role of actors in urban adaptation path-breaking
Buildings & CitiesDespite the growing demands in what urban adaptation (policy) is expected to address (e.g. systemic injustices), incremental responses are the norm. The role of different actors is investigated for maintaining and breaking path-dependencies in Atlanta ...
Julia Teebken
doaj +1 more source
« Histoires perturbées, passés retrouvés », une introduction
Conserveries Mémorielles, 2022 This introductory paper outlines the conceptual framework and case studies comprising the research project Disrupted Histories, Recovered Pasts. Our project proposes a cross-disciplinary analysis and cross-case synthesis of experience and memory in post ...
Sian Sullivan +4 more
doaj
Tidal Disruption of White Dwarfs from Ultra-close Encounters with Intermediate-mass Spinning Black Holes [PDF]
, 2012 We present numerical relativity results of tidal disruptions of white dwarfs from ultra-close encounters with a spinning, intermediate-mass black hole (IMBH). These encounters require a full general relativistic treatment of gravity.
Bode, Tanja +3 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fab five: pioneering sociocultural influence within the culture of basketball and American society
Frontiers in Sports and Active LivingDating back to when the inventor of the game, James Naismith, developed a mentoring relationship with John McClendon one of the African American pioneers in basketball (founder of the “fast-break”), there are countless examples of these intersections ...
M. Fennell +9 more
doaj +1 more source
The relationships between technology and open education in the development of a resilient higher education [PDF]
, 2010 The place of technology in the development of coherent educational responses to environmental and socio-economic disruption is here placed under scrutiny. One emerging area of interest is the role of technology in addressing more complex learning futures,
Hall, Richard, Winn, Joss
core +1 more source
Abundance Anomalies In Tidal Disruption Events
, 2015 The ~10% of tidal disruption events (TDEs) due to stars more massive than the Sun should show abundance anomalies due to stellar evolution in helium, carbon and nitrogen, but not oxygen.
Kochanek, C. S.
core +1 more source