Results 101 to 110 of about 1,458,434 (297)

Disruption management in passenger railway transportation. [PDF]

open access: yes
This paper deals with disruption management in passengerrailway transportation. In the disruption management process, manyactors belonging to different organizations play a role.
Potthoff, D.   +6 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Disrupt and unlock? The role of actors in urban adaptation path-breaking

open access: yesBuildings & Cities
Despite the growing demands in what urban adaptation (policy) is expected to address (e.g. systemic injustices), incremental responses are the norm. The role of different actors is investigated for maintaining and breaking path-dependencies in Atlanta ...
Julia Teebken
doaj   +1 more source

« Histoires perturbées, passés retrouvés », une introduction

open access: yesConserveries Mémorielles, 2022
This introductory paper outlines the conceptual framework and case studies comprising the research project Disrupted Histories, Recovered Pasts. Our project proposes a cross-disciplinary analysis and cross-case synthesis of experience and memory in post ...
Sian Sullivan   +4 more
doaj  

Alternative methods of microorganism disruption for agricultural applications

open access: yes, 2014
This paper reviews various non-conventional techniques for microorganism disruption. Microorganism disruption plays a pivotal role in various agricultural applications such as disinfection of irrigation water, processing of crops and livestock products ...
Al-Juboori, Raed A., Yusaf, Talal
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Fab five: pioneering sociocultural influence within the culture of basketball and American society

open access: yesFrontiers in Sports and Active Living
Dating back to when the inventor of the game, James Naismith, developed a mentoring relationship with John McClendon one of the African American pioneers in basketball (founder of the “fast-break”), there are countless examples of these intersections ...
M. Fennell   +9 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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