Results 51 to 60 of about 147,390 (303)
Plasmoid drift and first wall heat deposition during ITER H-mode dual-SPIs in JOREK simulations
Nuclear FusionThe heat flux mitigation during the thermal quench (TQ) by the shattered pellet injection (SPI) is one of the major elements of disruption mitigation strategy for ITER.
D. Hu +8 more
doaj +1 more source
Assessing Supply Chain Resilience to Mitigate Disruption: The Focus on Cross-Border Suppliers
LogisticsBackground: Cross-border suppliers have always been points of disruption, further impacting international trade, businesses, and societies along the chain. Understanding the current resilience capabilities of cross-border suppliers is a stepping-stone to
Ruth Banomyong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Nuclear FusionJOREK 3D non-linear magnetohydrodynamic simulations with non-equilibrium impurity treatment of thermal quench (TQ) triggered by a massive neon gas in EAST L-mode disruptions are first presented.
W. Xia +23 more
doaj +1 more source
TOKES studies of the thermal quench heat load reduction in mitigated ITER disruptions
Nuclear Materials and Energy, 2017 Disruption mitigation by massive gas injection (MGI) of Ne gas has been simulated using the 3D TOKES code that includes the injectors of the Disruption Mitigation System (DMS) as it will be implemented in ITER.
S. Pestchanyi +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Recent Advances in Multi-Dimensional Vibration Mitigation Materials and Devices
Frontiers in Materials, 2019 Harmful vibrations can cause many engineering problems, such as disasters of civil engineering structures, failure of precision equipment, and the disruption of some spacecraft components.
Zhao-Dong Xu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Interpretative 3D MHD modelling of deuterium SPI into a JET H-mode plasma
Nuclear FusionThe pre-thermal quench (pre-TQ) dynamics of a pure deuterium ( $\mathrm{D}_2$ ) shattered pellet injection (SPI) into a $3\,\mathrm{MA}$ / $7\,\mathrm{MJ}$ JET H-mode plasma is studied via 3D non-linear MHD modelling with the JOREK code.
M. Kong +28 more
doaj +1 more source
Recent ASDEX Upgrade research in support of ITER and DEMO [PDF]
, 2015 Recent experiments on the ASDEX Upgrade tokamak aim at improving the physics base for ITER and DEMO to aid the machine design and prepare efficient operation. Type I edge localized mode (ELM) mitigation using resonant magnetic perturbations (RMPs) has
García Muñoz, Manuel +4 more
core +1 more source