Results 41 to 50 of about 889,606 (319)

Size-Optimized Microspace Culture Facilitates Differentiation of Mouse Induced Pluripotent Stem Cells into Osteoid-Rich Bone Constructs

Stem Cells International, 2020
Microspace culture is promising for self-organization of induced pluripotent stem cells (iPSCs). However, the optimal size of microspaces for osteogenic differentiation is unclear.
Phoonsuk Limraksasin, Hiroko Okawa, Maolin Zhang, Takeru Kondo, Thanaphum Osathanon, Prasit Pavasant, Hiroshi Egusa   +6 more
doaj   +1 more source

Fibroblast growth factor stimulates photoreceptor differentiation in vitro

Journal of Neuroscience, 1992
Dissociated newborn rat retinal cells were maintained in monolayer culture for periods of up to 11 d. When grown in the absence of exogenous growth factors, 1–2% of the total neuronal population expressed opsin (the photopigment that is specific for ...
David Hicks, Y. Courtois
semanticscholar   +1 more source

Induced in Vitro Differentiation of β-Tubulin III Expressed Cells from Human Amniotic Epithelial Cells [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: The differentiation of neural cells from embryonic stem cells is influenced by several factors. Amniotic epithelial cells (AECs) share many of the same characteristics as embryonic stem cells, and therefore, those factors may ...
H. Niknejad, H. Peirovi, B. Jamber Nooshin, A. Ahmadiani, J. Ghanavi, M. Jorjani   +5 more
doaj   +2 more sources

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

Stem Cell Research & Therapy, 2018
Background Pancreatic progenitors (PPs) co-expressing the two transcription factors (TFs) PDX1 and NKX6.1 are recognized as the indispensable precursors of functional pancreatic β cells.
Bushra Memon, Manale Karam, Sara Al-Khawaga, Essam M. Abdelalim   +3 more
doaj   +1 more source

Induction of Cell Proliferation by Fibroblast and Insulin-Like Growth Factors in Pure Rat Inner Ear Epithelial Cell Cultures

Journal of Neuroscience, 1997
Proliferation of supporting cells in the inner ear is the early major event occurring during hair cell regeneration after acoustic trauma or aminoglycoside treatment.
J. L. Zheng, C. Helbig, Wei-qiang Gao, A. Rosenthal, J. Winslow   +4 more
semanticscholar   +1 more source

Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]

, 2010
There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G., An, J., Anderson, M., Beckhouse, A.G., Bellette, B., Bennebroek, M., Cecil, R., Chalk, A.M., Cochrane, J., Cook, A.L., Fan, Y., Féron, F., Mackay-Sim, A., Mahler, S., Matigian, N., McCurdy, R., McGrath, J.J., Mellick, G.D., Murrell, W., Nouwens, A., Perry, C., Raju, J., Ravishankar, S., Silburn, P.A., Sue, C.M., Sutharsan, R., Sutherland, G.T., Vitale, A.M., Wells, C.A., Wood, S.A.   +29 more
core   +1 more source

A plant-derived glucocorticoid receptor modulator attenuates inflammation without provoking ligand-induced resistance [PDF]

, 2010
Background: Acquired resistance to glucocorticoids constitutes a major clinical challenge, often overlooked in the search for improved alternatives to classic steroids.
De Bosscher, Karolien, Dewint, Pieter, Elewaut, Dirk, Gossye, Valerie, Haegeman, Guy, Van Beneden, Katrien   +5 more
core   +2 more sources

Survival of Purified Rat Photoreceptors In Vitro Is Stimulated Directly by Fibroblast Growth Factor-2

Journal of Neuroscience, 1998
Basic fibroblast growth factor (FGF-2) influences the differentiation and survival of retinal photoreceptors in vivo and in vitro, but it is not known whether it acts directly on photoreceptor FGF receptors or indirectly through activation of surrounding
V. Fontaine, N. Kinkl, J. Sahel, H. Dreyfus, D. Hicks   +4 more
semanticscholar   +1 more source

Co-expression networks in generation of induced pluripotent stem cells. [PDF]

, 2016
We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for
Coppola, Giovanni, Dansithong, Warunee, Figueroa, Karla P, Gao, Fuying, Paul, Sharan, Pflieger, Lance, Pulst, Stefan M   +6 more
core   +2 more sources

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides [PDF]

, 2020
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date.
Grabarics, Márkó, Guimond, Scott E., Hofmann, Johanna, Manz, Christian, Miller, Rebecca L., Pagel, Kevin, Schwörer, Ralf, Tyler, Peter C., Xu, Yongmei [u.v.m.], Zubkova, Olga V.   +9 more
core   +1 more source