Results 81 to 90 of about 1,227,945 (330)

Scapulothoracic dissociation

The British Journal of Radiology, 2019
Scapulothoracic dissociation is a rare and potentially limb- and life-threatening injury, that results from high-energy trauma. Scapulothoracic dissociation has the potential to be overlooked in the acute setting, especially in the setting of polytrauma. Therefore, a careful search for this condition should be performed in all patients with high-energy
Kimia Khalatbari, Kani, Felix S, Chew
openaire   +3 more sources

Recurrent Dissociative Fugue [PDF]

Indian Journal of Psychological Medicine, 2013
Dissociative fugue is a rarely reported diagnostic entity. It is one of the least understood and yet clinically one of the most fascinating disorders in mental health. Here, we describe a case of fugue in a 32-year-old man who was brought to mental hospital with complete loss of memory for events pertaining to identity of self.
Abhishek Mamarde, Praveen Navkhare, Amrita Singam, Akash Kanoje   +3 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Dissociative Adsorption: A Solvable Model

, 1993
A model of "hot"-dimer deposition in one dimension, introduced by Pereyra and Albano, is modified to have an unbounded dissociation range. The resulting dynamical equations are solved exactly. A related k-mer dissociation model is also introduced and its
Kuzovkov V, Liggett T, Pereyra V D, V Privman   +3 more
core   +2 more sources

Atrial Dissociation

Japanese Heart Journal, 1976
Atrial dissociation was recorded in a patient with malignant hypertension and microangiopathic hemolytic anemia. Digitalis intoxication was considered the cause of atrial dissociation.
N, Akatsuka, T, Maekawa, M, Hiraoka
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events

, 2004
L-selectin mediated tethers result in leukocyte rolling only above a threshold in shear. Here we present biophysical modeling based on recently published data from flow chamber experiments (Dwir et al., J. Cell Biol.
Alon, Alon, Bell, Chan, Chang, Chen, de Ch  teau, Doggett, Erdmann, Evans, Finger, Greenberg, Hynes, Kansas, Kucik, Marshall, Nicholson, Pavalko, R. Alon, Shao, Shoup, Springer, U. S. Schwarz   +22 more
core   +2 more sources

Machine learning methods for developments of binding kinetic models in predicting protein‐ligand dissociation rate constants [PDF]

, 2023
Yujing Zhao, Qilei Liu, Jian Du, Qingwei Meng, Lei Zhang   +4 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

State dissociation moderates response to dialectical behavior therapy for posttraumatic stress disorder in women with and without borderline personality disorder

European Journal of Psychotraumatology, 2016
Background: Patients with posttraumatic stress disorder (PTSD) are prone to dissociation, which in theory should interfere with successful treatment. However, most empirical studies do not substantiate this assumption.
Nikolaus Kleindienst, Kathlen Priebe, Nora Görg, Anne Dyer, Regina Steil, Lisa Lyssenko, Dorina Winter, Christian Schmahl, Martin Bohus   +8 more
doaj   +1 more source