Results 101 to 110 of about 226,875 (303)
PLoS ONE, 2011 To understand the underlying mechanisms of significant differences in dissociation rate constant among different inhibitors for HIV-1 protease, we performed steered molecular dynamics (SMD) simulations to analyze the entire dissociation processes of ...
Dechang Li +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
wiley +1 more source
New approach for studying macromolecular-ligand binding. Determination of the dissociation constant for macromolecule-bound ligand by gel filtration. [PDF]
, 1980 A graph is presented which permits facile determination of the dissociation constant constant for a macromolecule . ligand complex from gel filtration results; it can be used without a detailed understanding of the remainder of the text.
Zeeberg, Barry
core +2 more sources
Utility of FRET in studies of membrane protein oligomerization: The concept of the effective dissociation constant. [PDF]
Biophys J, 2023 McKenzie DM +3 more
europepmc +1 more source
Karl Popper and the Mechanisms of Hydrogen Embrittlement
Advanced Engineering Materials, EarlyView.Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley +1 more source
Equilibrium dissociation constant of CXCL12 for HP, HS and DS [PDF]
, 2013 The equilibrium levels of bound CXCL12 were extracted from the sensorgrams of Fig. 2 at the end of the association phases (apart from the lowest CXCL12 concentrations, which in some cases did not reach equilibrium) and used to calculate the dissociation ...
Patricia Rueda (35738) +6 more
core +1 more source
ReDirection: an R-package to compute the probable dissociation constant for every reaction of a user-defined biochemical network. [PDF]
Front Mol Biosci, 2023 Kundu S.
europepmc +1 more source
Microstructure Evolution of a VMnFeCoNi High‐Entropy Alloy After Synthesis, Swaging, and Annealing
Advanced Engineering Materials, EarlyView.The synthesis and processing (rotary swaging and annealing) of the novel VMnFeCoNi alloy is investigated, alongside the estimation of the grain size effect on hardness. Analysis of a wide grain size range of recrystallized microstructures (12–210 µm) reveals a low annealing twin density.
Aditya Srinivasan Tirunilai +6 more
wiley +1 more source
Creep Properties and Deformation Mechanism of Additively Manufactured NiAl‐CrMo Composites
Advanced Engineering Materials, EarlyView.Additively manufactured NiAl‐CrMo composites contain numerous interfaces and cell boundaries that control their creep response. At 700°C under high applied stress, creep is dominated by dislocation‐controlled power‐law mechanisms. At 800°C–900°C and lower stresses, creep is primarily diffusion‐controlled along cell boundaries.
Jan Vollhüter +9 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Reproduction of stacking fault energy calculations from literature with a semi‐automated large language model‐assisted extraction procedure: extraction of simulation protocol, atomistic structures, computational parameters, and reported results, ontology alignment, knowledge graph construction and, finally, recomputation forvalidation.
Sepideh Baghaee Ravari +5 more
wiley +1 more source