Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves
Despite the central role that antibodies play in the adaptive immune system and in biotechnology, much remains unknown about the quantitative relationship between an antibody’s amino acid sequence and its antigen binding affinity.
Rhys M Adams +3 more
doaj +1 more source
Determination of the Dissociation Constant for Polyvalent Receptors Using ELISA: A Case of M13 Phages Displaying Troponin T-Specific Peptides. [PDF]
Machera SJ +3 more
europepmc +1 more source
In MOCVD MoS2 memristors, a current compliance‐regulated Ag filament mechanism is revealed. The filament ruptures spontaneously during volatile switching, while subsequent growth proceeds vertically through the MoS2 layers and then laterally along the van der Waals gaps during nonvolatile switching.
Yuan Fa +19 more
wiley +1 more source
Chronopotentiometric Evaluation of Ionization Degree and Dissociation Constant of Imidazolium-Based Ionic Liquid [C6Meim][NTf2] in Polymeric Plasticized Membranes. [PDF]
Pokhvishcheva NV +5 more
europepmc +1 more source
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Dissociation Constant of Integrin-RGD Binding in Live Cells from Automated Micropipette and Label-Free Optical Data. [PDF]
Gerecsei T +7 more
europepmc +1 more source
This work presents a closed‐loop optimization workflow integrating CatBot, an automated synthesis and testing system, to discover NiMo hydrogen‐evolution catalysts. CatBot synthesised and evaluated 228 unique samples, identifying the best performing catalysts for transfer to nickel‐foam electrodes. The best candidate is highly active, reaching 1 Acm−2${
Paolo Vincenzo Freiesleben de Blasio +7 more
wiley +1 more source
Kinetic Analysis of a Protein-protein Complex to Determine its Dissociation Constant (KD) and the Effective Concentration (EC50) of an Interplaying Effector Molecule Using Bio-layer Interferometry. [PDF]
Orthwein T +3 more
europepmc +1 more source
The dissociation constants of diethanolamine (2:2'-dihydroxydiethylamine) and its conjugate acid were determined by electromotive force measurements of the cell [formula] in the temperature range 0 to 50 °C. The acidic dissociation constant (Kbh) of the
Bower, Vincent E.; Robinson, Robert A.; Bates, Roger G.
core +1 more source
Fiber‐Based Wearable Electronics as Adaptive Biointerfaces for Healthcare Applications
Fiber‐based wearable electronics have been extensively studied as adaptive healthcare biointerfaces. In this review, we classify and introduce fiber‐based systems according to biointerface design, conductive materials, transduction mechanisms, and healthcare applications, and provide a perspective on their translation toward reliable, continuous ...
Sangwoo Hong +5 more
wiley +1 more source

