Results 81 to 90 of about 1,894,770 (297)

Dissociation constant of anisic (p-methoxybenzoic) acid in the system ethanol-water at 25 C

open access: yes, 1960
The dissociation constant of anisic (p-methoxybenzoic) acid in the system ethanol-water was measured at 25 C by a combination of spectrophotometric and electrometric methods. Percentage by weight of ethanol in the solvent system varied from zero to 83.43.
Sager, Elizabeth E.; Bower, Vincent E.
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Determination of the dissociation constants of some newly synthesized derivatives of 1,2,4-triazoline-3-thione in sodium hydroxide media

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2006
The behaviour of some newly synthesized derivatives of 1,2,4-triazoline-3-thione (4-butyl-5-octyl-2,4-dihydro-3H-1,2,4-triazoline-3-thione, 4-allyl-5-octyl-2,4-dihydro-3H-1,2,4-triazoline-3-thione, 4-phenyl-5-octyl-2,4- dihydro-3H-1,2,4-triazoline-3 ...
Mirjana Jankulovska   +2 more
doaj  

Strength of hydrogen bond network takes crucial roles in the dissociation process of inhibitors from the HIV-1 protease binding pocket.

open access: yesPLoS ONE, 2011
To understand the underlying mechanisms of significant differences in dissociation rate constant among different inhibitors for HIV-1 protease, we performed steered molecular dynamics (SMD) simulations to analyze the entire dissociation processes of ...
Dechang Li   +3 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Apparent Dissociation Constant of a Porphyrin

open access: yes, 2023
The purpose of this laboratory is to determine the apparent acid dissociation constant, a, by estimating the pa value of a porphyrin using visible spectrophotometry.
Ballester, Maria, Castro, Victor
core   +1 more source

Dissociation Rate Calculation via Constant-Force Steered Molecular Dynamics Simulation

open access: yes
Steered molecular dynamics (SMD) simulations are used to study molecular dissociation events by applying a harmonic force to the molecules and pulling them at a constant velocity.
Shinji Iida (6495608)   +1 more
core   +1 more source

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