Results 61 to 70 of about 1,952,840 (306)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Interaction of GB1 with Metal Ions Studied by NMR Spectroscopy
Chinese Journal of Magnetic Resonance, 2018 B1 domain of staphylococcal protein G (GB1) is a widely used model protein for developing in vivo and in vitro protein structural determination methods based on paramagnetic nuclear magnetic resonance (NMR) such as pseudocontact chemical shift (PCS) and ...
CHENG Kai +3 more
doaj +1 more source
Dissociation constant (Kd) of PNP-AV binding to cells.
, 2013 Dissociation constant (Kd) of PNP-AV binding to cells.
John J. Krais (466121) +2 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Physiological Reports, 2021 The purpose of this investigation was to present calculations of fractional H+ exchange (~H+e) from the chemical reactions of non‐mitochondrial energy catabolism.
Robert A. Robergs
doaj +1 more source
Apparent Dissociation Constant of a Porphyrin
, 2023 The purpose of this laboratory is to determine the apparent acid dissociation constant, a, by estimating the pa value of a porphyrin using visible spectrophotometry.
Ballester, Maria, Castro, Victor
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Spring constant regulate selectin-ligand bond dissociation
, 2013 Forced dissociation of selectin-ligand complex is crucial to such biological processes as leukocyte recruitment,thrombosis formation,as well as tumor metastasis~[1].Although several assays and techniques,e.g.,dynamic force spectroscopy(DFS),have been ...
孙淦云, 吕守芹, 龙勉, 章燕
core +2 more sources
The dissociation constant of aptamer binding to C4-HSL by saturation binding mode.
, 2019 The dissociation constant of aptamer binding to C4-HSL by saturation binding mode.
Meng Zhao (54299) +4 more
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source