Results 51 to 60 of about 226,875 (303)
Distribution of dissociation constant values of muscarinic agonists [PDF]
, 1989 The frequency distributions of dissociation constant values of some muscarinic agonists (carbachol, muscarone and cis-2-methyl-5-trimethylammoniummethyl-1,3-oxathiolane) obtained on guinea-pig ileum and atria and rat urinary bladder have been examined to
Enzo Grana +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Determination of dissociation constant of alkaloids by gradient elution system using UPLC [PDF]
, 2007 Dissociation constant is a very important physical chemical parameter to the compounds. It contributes to an understanding of many phenomena such as reaction rates, biological uptake, transport, environmental fate. There are many methods to determine the
金郁, 肖远胜, 张静, 梁鑫淼
core
Biosensors, 2020 Affinity characterization is essential to develop reliable aptamers for tumor biomarker detection. For alpha-fetoprotein (AFP), a biomarker of hepatocellular carcinoma (HCC), two DNA aptamers were described with very different affinity.
Ramón Lorenzo-Gómez +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Direct Potentiometric Determination of Fluoride Species by Using Ion-Selective Fluoride Electrode
International Journal of Electrochemical Science, 2012 A novel approach and method for potentiometric determination of acid dissociation constant (Ka) of hydrofluoric acid are described. Proposed method is based on using commercial fluoride ISE (FISE) as very inexpensive, simple and reasonably fast method ...
Ante Prkić +3 more
doaj +1 more source
Potentiometric investigation of acid-base equilibria of two new pyrimidine derivatives in various methanol-water media [PDF]
Journal of the Serbian Chemical Society, 2006 The acid-base properties of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-one (L1) and 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione (L2) were investigated potentiometrically at an ionic strength of 0.10M(LiCl) in 19.8, 33.6 and 55.9 % (v/v) methanol ...
Kiliç Hasan, Birol Er
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dissociation Rate Calculation via Constant-Force Steered Molecular Dynamics Simulation [PDF]
Steered molecular dynamics (SMD) simulations are used to study molecular dissociation events by applying a harmonic force to the molecules and pulling them at a constant velocity.
Shinji Iida (6495608) +1 more
core +1 more source
Computer programs for calculating pKa: a comparative study for 3-(3-(2-nitrophenyl)prop-2-enoyl)-2H-1-benzopyran-2-one [PDF]
Journal of the Serbian Chemical Society, 2010 Coumarin-based compounds containing a chalcone moiety exhibit antimicrobial activity. These substances are potential drugs and it is important to determine their pKa values. However, they are almost insoluble in water.
SELMA ŠPIRTOVIĆ-HALILOVIĆ +1 more
doaj