Results 31 to 40 of about 1,952,840 (306)

Dissociation experiment and dissociation rate model of CO2 hydrate

open access: yesNatural Gas Industry B, 2021
Applying CO2 hydrate (referred to as hydrate) to CO2 storage and sequestration can alleviate global greenhouse effect, which is currently a hot spot of hydrate research.
Xuewen Cao   +4 more
doaj   +1 more source

Dissociation of nitrophenols in pyridine. Thermodynamic dissociation constant and homoconjugation constant.

open access: yesNIPPON KAGAKU KAISHI, 1988
ピリジン中での酸の解離機構を解明する目的で,ピリジンを溶媒としてニトロフェノール類の電気伝導度測定およびこれらのカリウム壇の溶解度測定を行なった。酸(HA)の解離としては,単純イオン対の解離平衡とホモ共役イオン(HA2-)の生成平衡を考え,単純イオン対の熱力学的解離定数およびホモ共役生成定数を決定した。酸の解離定数はニトロ基の置換数に比例して大きくなり,酸の強さの序列は,ピクリン酸>2,4-ジニトロフェノール(2,4-DNP)>2,6-DNP>2,5-DNPおよびp-ニトロフェノール(p-NP)>ο-NP>m-NPであった。メタ位にニトロ基が置換したフェノールは,解離が低いばかりでなくホモ共役体を形成しやすく,ピクリン酸や2,4および2,6-DNPはほとんどホモ共役体を形成しないことが認められた ...
Isao YAMAKAWA, Toyohiko NAKAJIMA
openaire   +2 more sources

The Dissociation Constants of Tetrahydrofolic Acid

open access: yesJournal of Biological Chemistry, 1966
Six dissociable groups exist in tetrahydrofolic acid in the range H0 -3.0 to pH 14. The assignments in tetrahydrofolic acid by titrimetric and spectrophotometric comparisons with model compounds, p-aminobenzoylglutamic acid and 2-amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinone, are as follows: acidic ionization of amide, pK' 10.5; N5, pK' 4.82; γ ...
R G, Kallen, W P, Jencks
openaire   +2 more sources

Determination of the dissociation constant of the HisF-HisH heterodimer at different temperatures using ITC.

open access: yes, 2022
Determination of the dissociation constant of the HisF-HisH heterodimer at different temperatures using ITC.
Vitor M. Almeida (4768668)   +2 more
core   +1 more source

Calculation of Crystal-Solution Dissociation Constants

open access: yesBiomolecules, 2022
The calculation of dissociation constants is an important problem in molecular biophysics. For such a calculation, it is important to correctly calculate both terms of the binding free energy; that is, the enthalpy and entropy of binding.
Sergiy O. Garbuzynskiy   +1 more
doaj   +1 more source

Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID‐19 and response to treatment

open access: yesPharmacology Research & Perspectives, 2022
Why a systems analysis view of this pandemic? The current pandemic has inflicted almost unimaginable grief, sorrow, loss, and terror at a global scale. One of the great ironies with the COVID‐19 pandemic, particularly early on, is counter intuitive.
Richard J. Head   +7 more
doaj   +1 more source

Relationship between inhibition % and dissociation constant (Kd).

open access: yes, 2015
Relationship between inhibition % and dissociation constant (Kd).
Hideki Maki (316193)   +7 more
core   +1 more source

Consideration of the contribution of chemical (non-enzymatic) conversion of substrate in the general mechanism of enzyme reaction [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2019
When enzyme-catalyzed reactions are studied, it is necessary to take into account the contribution of the chemical (non-enzymatic) conversion of the substrate to the product, which is carried out together with the enzyme-catalyzed conversion of the ...
S. O. Kosterin   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Generation of Red-Shifted Cameleons for Imaging Ca2+ Dynamics of the Endoplasmic Reticulum

open access: yesSensors, 2015
Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca2+ signals. The probes are based on Förster resonance energy transfer (FRET) between terminally located fluorescent proteins (FPs), which move together ...
Markus Waldeck-Weiermair   +12 more
doaj   +1 more source

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