Results 11 to 20 of about 1,952,840 (306)
The acid dissociation constant of triethylsilanol in aqueous solution
CHIMIA, 1974 The acid dissociation constant of (C2H5)3SiOH in aqueous solution was evaluated with the aid of a distribution method using CCl4 and an aqueous phase of constant ionic strength as solvents. The experimental results led to a value of pKa = 13.63 (± 0.07)
H. Arm, K. Hochstrasser, P.W. Schindler
doaj +2 more sources
The Dissociation Constant of Eugenol.
, 1935 The Dissociation Constant of Eugenol.
GADIYARA GUNDU RAO
openaire +2 more sources
Dissociation Rate Calculation via Constant-force Steered Molecular Dynamics Simulation [PDF]
, 2022 Steered molecular dynamics (SMD) simulations have been applied to molecular dissociation events by adding a harmonic force to molecules. Further, molecules are pulled at a constant velocity.
Shinji, Iida, Tomoshi, Kameda
core +1 more source
Prediction of Dissociation Constant in Protein-Ligand Interaction [PDF]
, 2021 In protein-ligand interactions, such as antigen-antibody interactions and hormone-receptor interactions, a correlation between the equilibrium dissociation constant KD and the reduced mass of the protein and ligand was found.
Masatoshi, Kawashima
core +1 more source
Thermodynamic formulation on Ostwald’s law of dilution and the acid dissociation constant Ka [PDF]
, 2022 The thermodynamic background of Ostwald’s law of dilution, which gives the acid dissociation constant (Ka), is revealed. The feature of Ka as a constant is understandable in the same context as the equilibrium shift of the gas reaction by pressure.
Yukiteru, Katsumoto, Yukiteru Katsumoto
core +2 more sources
Accuracy Assessment for Equilibrium Dissociation Constant Using a Single Binding Isotherm [PDF]
, 2023 The equilibrium dissociation constant (Kd) characterizes stability of non-covalent molecular complexes. Determining Kd for highly stable complexes may be extremely inaccurate if the ratio between the concentration of the limiting component (L0) and the a
Sergey, Krylov +3 more
core +1 more source
Molecules, 2022 The microscale thermophoresis (MST) technique was utilized to investigate lactoferrin–drug interaction with the iron chelator, deferiprone, using label-free system. MST depends on the intrinsic fluorescence of one interacting partner.
Mufarreh Asmari +7 more
doaj +1 more source
What Does the Accuracy of the Equilibrium Dissociation Constant of Affinity Complexes Depend on Fundamentally? [PDF]
, 2023 The equilibrium dissociation constant (Kd) characterizes stability of binding complexes. The classic way of Kd determination involves finding the dependence of a fraction of unbound ligand on the total concentration of target (T0) when the total ...
Sergey, Krylov +6 more
core +2 more sources
Molecules, 2023 The interaction between SARS-CoV-2 spike RBD and ACE2 proteins is a crucial step for host cell infection by the virus. Without it, the entire virion entrance mechanism is compromised.
Jason Fauquet +4 more
doaj +1 more source
Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption
eLife, 2014 70-kDa Heat shock proteins are ATP-driven molecular chaperones that perform a myriad of essential cellular tasks. Although structural and biochemical studies have shed some light on their functional mechanism, the fundamental issue of the role of energy ...
Paolo De Los Rios, Alessandro Barducci
doaj +1 more source