Results 21 to 30 of about 1,894,770 (297)
What Does the Accuracy of the Equilibrium Dissociation Constant of Affinity Complexes Depend on Fundamentally? [PDF]
, 2023 The equilibrium dissociation constant (Kd) characterizes stability of binding complexes. The classic way of Kd determination involves finding the dependence of a fraction of unbound ligand on the total concentration of target (T0) when the total ...
Sergey, Krylov +6 more
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Spectrophotometric determination of dissociation constant
, 2022 Vrijednost konstante disocijacije kiseline nam govori o stupnju disocijacije kiseline, odnosno o odnosu ravnotežnih koncentracija disociranog i nedisociranog oblika molekule.
Orešković, Patrik
core +3 more sources
Molecules, 2023 The interaction between SARS-CoV-2 spike RBD and ACE2 proteins is a crucial step for host cell infection by the virus. Without it, the entire virion entrance mechanism is compromised.
Jason Fauquet +4 more
doaj +1 more source
Spring constant regulate selectin-ligand bond dissociation
, 2013 Forced dissociation of selectin-ligand complex is crucial to such biological processes as leukocyte recruitment,thrombosis formation,as well as tumor metastasis~[1].Although several assays and techniques,e.g.,dynamic force spectroscopy(DFS),have been ...
孙淦云, 吕守芹, 龙勉, 章燕
core +4 more sources
Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption
eLife, 2014 70-kDa Heat shock proteins are ATP-driven molecular chaperones that perform a myriad of essential cellular tasks. Although structural and biochemical studies have shed some light on their functional mechanism, the fundamental issue of the role of energy ...
Paolo De Los Rios, Alessandro Barducci
doaj +1 more source
Cells, 2022 Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand +10 more
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Acid dissociation constants of glycopeptides [PDF]
Biochemical Journal, 1977 Glycopeptides containing mainly four amino acid residues in the sequence Asn-Leu-Thr-Ser, with small amounts of additional amino acid residues, were isolated from enzymic hydrolysates of hen's-egg albumin. Heterogeneity of the carbohydrate moiety was confirmed. Acid-base titrations showed that the alpha-amino group has a pKa value of 6.43 at 25 degrees
B M, Austen, R D, Marshall
openaire +2 more sources
Química Nova, 2011 This paper presents the determination of the dissociation constant (Ka) of captopril and nimesulide as contextualized experiments to teach chemical concepts to students of Pharmacy.
Airton Vicente Pereira +3 more
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Determination of Acid Dissociation Constants of Some 2-(3H) –Benzoxazolone Derivatives by UV–Vis Spectrophotometry [PDF]
Iranian Journal of Chemistry & Chemical EngineeringThe acid dissociation constant values of some 2-(3H)-benzoxazolone derivatives were determined in buffered solutions by using the UV-Vis spectrophotometric method.
Semra Altunterim Erkan +2 more
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In vitro Microtubule Binding Assay and Dissociation Constant Estimation
Bio-Protocol, 2016 Microtubules (MTs) support an astonishing set of versatile cellular functions ranging from cell division, vesicle transport, and cell and tissue morphogenesis in various organisms.
Christopher Kesten +2 more
doaj +1 more source