Results 21 to 30 of about 226,875 (303)

Contribution to the Understanding of the Interaction between a Polydopamine Molecular Imprint and a Protein Model: Ionic Strength and pH Effect Investigation

Sensors, 2021
Several studies were devoted to the design of molecularly imprinted polymer (MIP)-based sensors for the detection of a given protein. Here, we bring elements that could contribute to the understanding of the interaction mechanism involved in the ...
Amal Tlili, Ghada Attia, Sohayb Khaoulani, Zouhour Mazouz, Chouki Zerrouki, Nourdin Yaakoubi, Ali Othmane, Najla Fourati   +7 more
doaj   +1 more source

Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant

Molecules, 2022
The microscale thermophoresis (MST) technique was utilized to investigate lactoferrin–drug interaction with the iron chelator, deferiprone, using label-free system. MST depends on the intrinsic fluorescence of one interacting partner.
Mufarreh Asmari, Muhammad Waqas, Adel Ehab Ibrahim, Sobia Ahsan Halim, Ajmal Khan, Ahmed Al-Harrasi, Hermann Wätzig, Sami El Deeb   +7 more
doaj   +1 more source

Microfluidic Diffusion Sizing Applied to the Study of Natural Products and Extracts That Modulate the SARS-CoV-2 Spike RBD/ACE2 Interaction

Molecules, 2023
The interaction between SARS-CoV-2 spike RBD and ACE2 proteins is a crucial step for host cell infection by the virus. Without it, the entire virion entrance mechanism is compromised.
Jason Fauquet, Julie Carette, Pierre Duez, Jiuliang Zhang, Amandine Nachtergael   +4 more
doaj   +1 more source

Acid dissociation constant and related thermodynamic quantities for triethanolammonium ion in water from 0 to 50 C [PDF]

, 1960
Earlier studies of the dissociation constants of monoethanolammonium and diethanolammonium ions and the thermodynamic constants for the dissociation processes have been supplemented by a similar study of triethanolammonium ion from 0 to 50 C.
Bates, Roger G.; Allen, Guy F.
core   +1 more source

Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption

eLife, 2014
70-kDa Heat shock proteins are ATP-driven molecular chaperones that perform a myriad of essential cellular tasks. Although structural and biochemical studies have shed some light on their functional mechanism, the fundamental issue of the role of energy ...
Paolo De Los Rios, Alessandro Barducci
doaj   +1 more source

Accelerated Evolution of Cytochrome c in Higher Primates, and Regulation of the Reaction between Cytochrome c and Cytochrome Oxidase by Phosphorylation

Cells, 2022
Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand, Martha Scharlau, Lois Geren, Marissa Hendrix, Clayre Parson, Tyler Elmendorf, Earl Neel, Kaila Pianalto, Jennifer Silva-Nash, Bill Durham, Francis Millett   +10 more
doaj   +1 more source

Acid dissociation constants of glycopeptides [PDF]

Biochemical Journal, 1977
Glycopeptides containing mainly four amino acid residues in the sequence Asn-Leu-Thr-Ser, with small amounts of additional amino acid residues, were isolated from enzymic hydrolysates of hen's-egg albumin. Heterogeneity of the carbohydrate moiety was confirmed. Acid-base titrations showed that the alpha-amino group has a pKa value of 6.43 at 25 degrees
B M, Austen, R D, Marshall
openaire   +2 more sources

Determinação da constante de dissociação (Ka) do captopril e da nimesulida: experimentos de química analítica para o curso de farmácia

Química Nova, 2011
This paper presents the determination of the dissociation constant (Ka) of captopril and nimesulide as contextualized experiments to teach chemical concepts to students of Pharmacy.
Airton Vicente Pereira, Aline Ansbach Garabeli, Grazieli Delponte Schunemann, Patrícia Cristine Borck   +3 more
doaj   +1 more source

Determination of Acid Dissociation Constants of Some 2-(3H) –Benzoxazolone Derivatives by UV–Vis Spectrophotometry [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The acid dissociation constant values of some 2-(3H)-benzoxazolone derivatives were determined in buffered solutions by using the UV-Vis spectrophotometric method.
Semra Altunterim Erkan, Hayati Celik, Banu Kesanlı   +2 more
doaj   +1 more source

Acidic dissociation of diprotonated piperazine in methanol-water solvents from 10 to 40 C [PDF]

, 1970
The first dissociation constant of piperazinium ion has been determined by the emf method in five methanol-water solvents (10 to 70 wt % MeOH) at 25 C and in three solvents (10, 20, and 50 wt % MeOH) from 10 to 40 C.
Paabo, Maya; Bates, Roger G.
core   +1 more source