Results 81 to 90 of about 525,078 (332)

Composition and Dissolution of a Migratory, Weathered Coal Tar Creosote DNAPL

Frontiers in Environmental Science, 2016
Opaque, viscous tars derived from the carbonization of fossile carbon feedstocks, such coal tars and creosote, are long-term sources of groundwater contamination, predominantly with poly- and heterocyclic aromatic hydrocarbons (PAH).
Kerstin E. Scherr, Kerstin E. Scherr, Viktoriya Vasilieva, Wolfgang Lantschbauer, Manfred Nahold   +4 more
doaj   +1 more source

Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol^® Enabled Amorphous Solid Dispersions

Pharmaceutics, 2020
Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies.
Urvi Gala, Dave Miller, Robert O. Williams   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Vacuum Brazing Ti–15–3 with a TiNiNb Braze Alloy

Metals, 2019
Among all types of brazing fillers, Ti-based fillers show satisfactory joint strengths in brazing titanium alloys. However, the major concern in using such fillers is the formation of Cu/Ni/Ti intermetallic compound(s) in the joint.
Chuan-Sheng Kao, Leu-Wen Tsay, Shan-Bo Wang, Ren-Kae Shiue   +3 more
doaj   +1 more source

Towards a molecular understanding of cellulose dissolution in ionic liquids: anion/cation effect, synergistic mechanism and physicochemical aspects

Chemical Science, 2018
This perspective summarizes mechanistic studies on cellulose dissolution in ionic liquids, highlighting the synergistic mechanism, physicochemical aspects and future research trends.
Yao Li, Jianji Wang, Xiaomin Liu, Suojiang Zhang   +3 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Effect of Soil Organic Matter, Soil pH, and Moisture Content on Solubility and Dissolution Rate of CuO NPs in Soil.

Environmental Science and Technology, 2019
The objectives of this research were to quantify the impact of organic matter content, soil pH and moisture content on the dissolution rate and solubility of copper oxide nanoparticles (CuO NPs) in soil, and to develop an empirical model to predict the ...
Xiaoyu Gao, S. Rodrigues, Eleanor Spielman-Sun, Sónia P. Lopes, Sandra Rodrigues, Yilin Zhang, A. Avellan, R. M. Duarte, A. Duarte, Elizabeth A. Casman, G. Lowry   +10 more
semanticscholar   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

First-Principles and Empirical Approaches to Predicting In Vitro Dissolution for Pharmaceutical Formulation and Process Development and for Product Release Testing

AAPS Journal, 2019
This manuscript represents the perspective of the Dissolution Working Group of the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) and of two focus groups of the American Association of Pharmaceutical Scientists ...
N. Zaborenko, Zhenqi Shi, Claudia C. Corredor, Brandye Smith-Goettler, Limin Zhang, Andre Hermans, C. Neu, Md Anik Alam, Michael J. Cohen, Xujin Lu, Leah Xiong, Brian M. Zacour   +11 more
semanticscholar   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source