Results 181 to 190 of about 56,903 (208)
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Improvement of the wettability and dissolution of fenofibrate compacts by plasma treatment
International Journal of Pharmaceutics, 2011The goal of this study was to investigate the effect of plasma treatment on the wettability and dissolution of fenofibrate compacts. Contact angle measurements and intrinsic dissolution rate studies of untreated and plasma-treated fenofibrate compacts were conducted.
Philipp, Buch +2 more
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Improving cystine stone therapy: an in vitro study of dissolution
Urology, 2000To perform an in vitro study analyzing the possibilities in therapeutic strategies for an effective treatment of cystine stones.Artificial stones made of cystine [Bon(n)-Stones] with a ball-shaped size of 0.9 cm in diameter were used. Chemolysis of artificial cystine stones with different solvents (artificial urine, physiologic sodium chloride solution,
D, Heimbach +3 more
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Improvement of clofibrate dissolution by complexation with cyclodextrin
International Journal of Pharmaceutics, 1996Abstract Inclusion complexes of clofibrate with β-cyclodextrin (βCD) were prepared by coprecipitation, kneading and sealed heating methods and characterized by UV spectrophotometry, differential scanning calorimetry, X-ray diffractometry and infrared spectroscopy. All results were in keeping with the formation of 1:1 inclusion complex.
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Improvement in the dissolution properties of theophylline with ß-cyclodextrin
2019An improvement in the dissolution of theophylline with beta-cyclodextrin was achieved by subjecting them to co-grinding and freeze-drying methods. The products obtained were examined by the phase solubility method, differential scanning calorimetry and X-ray diffractometry.
Yazan, Y, Sumnu, M
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Improved Dissolution of Indomethacin in Coprecipitates with Phospholipids-II
Drug Development and Industrial Pharmacy, 1993AbstractIndomethacin powders were blended with phospholipids to prepare physical mixtures or made into solid dispersions by the solvent method and their comparative dissolution profiles were studied. Indomethacin exhibited significantly improved dissolution rates in phospholipid coprecipitates compared to either the physical mixtures or the pure ...
Gopal K. Potti +4 more
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AAPS PharmSciTech
Natural lipophilic pigments typically exhibit poor water solubility, low dissolution rates, and photothermal instability, which hinder their pharmaceutical application. To address these challenges, a nanosuspension-microencapsulation delivery system was developed using curcumin (CUR) and lutein (LUT) as model compounds to enhance dissolution and ...
Zhitao Cai +8 more
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Natural lipophilic pigments typically exhibit poor water solubility, low dissolution rates, and photothermal instability, which hinder their pharmaceutical application. To address these challenges, a nanosuspension-microencapsulation delivery system was developed using curcumin (CUR) and lutein (LUT) as model compounds to enhance dissolution and ...
Zhitao Cai +8 more
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Improved Dissolution Characteristics of Silymarin and Their Bioavailability in Rats
Journal of Korean Pharmaceutical Sciences, 2003Silybin is the main component of Cardus marianus extracts originated from Silybum marianum and has a hepato-protective effect. It is a water-insoluble compound and poorly absorbed from the gastrointestinal tract, resulting in very low oral bioavailability(BA).
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Co-precipitates of lumefantrine-Eudragit E PO for dissolution improvement
Annales Pharmaceutiques Francaises, 2022Sarika Wairkar
exaly
Validation of an Improved Wood’s Rotating Disk Dissolution Apparatus
Journal of Pharmaceutical Sciences, 1993R N, Jashnani, P R, Byron, R N, Dalby
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