Results 161 to 170 of about 56,903 (208)

Comparative evaluation of ternary amorphous solid dispersions: Identifying optimal excipient systems for enhancing drug solubility. [PDF]

open access: yesInt J Pharm X
Budiman A   +9 more
europepmc   +1 more source
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Characteristics of Bicalutamide Solid Dispersions and Improvement of the Dissolution

Drug Development and Industrial Pharmacy, 2006
The purpose of our study was to formulate and evaluate bicalutamide (BL) solid dispersions (SD). The physicochemical properties were evaluated by differential scanning calorimetry (DSC), Fourier-Transform infrared (FT-IR) spectroscopy, Powder X-ray diffractometry (PXRD), dissolution studies, and stability studies.
Fuzheng Ren   +2 more
exaly   +3 more sources

Characterization of ibuprofen microparticle and improvement of the dissolution

Pharmaceutical Development and Technology, 2016
The objective of this study was to prepare ibuprofen (IBP) microparticles by pH-change method and enhance the dissolution rate in vitro. Tween80 and Cremophor RH40 were selected as stabilizers to change the microparticles morphology. The microparticles were evaluated by dissolution profiles and characterized by differential scanning calorimetry (DSC ...
Fuzheng, Ren   +5 more
openaire   +2 more sources

Improved Dissolution Rate of Indomethacin by Adsorbents

Drug Development and Industrial Pharmacy, 1998
Samples of indomethacin and kaolin or microcrystalline cellulose (Avicel) were prepared by solvent deposition or simple blending methods. Dissolution rates of these samples were studied. The surface adsorption of indomethacin on the studied adsorbents was shown to improve the dissolution rate of the drug in water.
S M, Alsaidan   +2 more
openaire   +2 more sources

Dissolution improvement of fenofibrate by melting inclusion in mesoporous silica

open access: yesAsian Journal of Pharmaceutical Sciences, 2013
In this study, using mesoporous silica for the solubility enhancement of poorly water-soluble drug was investigated. Although the incorporating drug into mesoporous silica is generally performed through the solvent method, the new melting method was ...
Waree Limwikrant, Kunikazu Moribe
exaly   +2 more sources

Accelerated dissolution testing for improved quality assurance

Journal of Pharmaceutical and Biomedical Analysis, 2002
In pharmaceutical production of controlled release tablets and capsules, a rapid and automated at-line dissolution test for quality assurance of semi-products is advantageous. For effective control of the production, the analysis should not take more than about an hour, without loss of correlation to the ordinary (USP) dissolution test of the final ...
Per Ola, Quist, Göran, Ostling
openaire   +2 more sources

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