Results 31 to 40 of about 2,889,262 (312)

Improvement of the Solubility and Dissolution Characteristics of Risperidone via Nanosuspension Formulations

Iraqi Journal of Pharmaceutical Sciences, 2022
Risperidone is an atypical antipsychotic drug that is used for treating schizophrenia, bipolar mania, and autism. Risperidone rebalances dopamine and serotonin to improve thinking, mood, and behavior by working on dopamine and serotonin α2receptor ...
Hayder Emad, Shaimaa Nazar Abd-Alhammid
doaj   +1 more source

Improvement of dissolution rate of indomethacin by inkjet printing

European Journal of Pharmaceutical Sciences, 2015
The aim of this study was to prepare printable inks of the poorly water soluble drug indomethacin (IMC), fabricate printed systems with flexible doses and investigate the effect of ink excipients on the printability, dissolution rate and the solid state properties of the drug.
Henrika, Wickström, Mirja, Palo, Karen, Rijckaert, Ruzica, Kolakovic, Johan O, Nyman, Anni, Määttänen, Petri, Ihalainen, Jouko, Peltonen, Natalja, Genina, Thomas, de Beer, Korbinian, Löbmann, Thomas, Rades, Niklas, Sandler   +12 more
openaire   +3 more sources

Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets

, 2015
The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three different buffer solutions (pH 1.2, 4.
Ozturk, Naile, Kaynak, Mustafa Sinan, Sahin, Selma   +2 more
core   +1 more source

Physicochemical Characterization and Dissolution Enhancement of Mefenamic Acid–Isonicotinamide Crystalline Solid Dispersion

Biology, Medicine & Natural Product Chemistry
Poor aqueous solubility limits the bioavailability of non-steroidal anti-inflammatory drugs like mefenamic acid. This study aims to improve the solubility and dissolution of mefenamic acid through crystalline solid dispersions using solvent evaporation ...
Indra Indra, Nurul Apriani, Ade Yeni Aprillia, Winda Trisna Wulandari, Gatut Ari Wardani, Firman Gustaman   +5 more
doaj   +1 more source

Using fluid bed granulation to improve the dissolution of poorly water-soluble drugs

Brazilian Archives of Biology and Technology, 2012
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and croscarmellose sodium and then ...
Andrea Ikeda Takahashi, Felipe Rebello Lourenço, Marcelo Dutra Duque, Vladi Olga Consiglieri, Humberto Gomes Ferraz   +4 more
doaj   +1 more source

Uv Spectrophotometric Method For Determination Of The Dissolution Profile Of Rivaroxaban

, 2014
Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in pharmaceutical formulations and the ...
Celebier, Mustafa, Kaynak, Mustafa Sinan, Sahin, Selma, Altinoz, Sacide   +3 more
core   +1 more source

Experimental determination of plagioclase dissolution rates as a function of its composition and pH at 22°C. [PDF]

, 2014
The steady-state, far-from-equilibrium dissolution rates of nine distinct plagioclases ranging in composition from An2 to An89 were measured in mixed flow reactors at 22 ± 2 C and pH from 2 to 11.
Gudbrandsson S., Wolff-Boenisch D., Gislason S. R. and Oelkers E. H.
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Cavitation-assisted decontamination of yttria from graphite of different densities

Ultrasonics Sonochemistry, 2021
Yttria coated graphite crucibles are widely used to handle molten refractory and radioactive metals like uranium and plutonium. However, the coated layer suffers damages like cracking and peeling off owing to thermal cycles.
S. Lahiri, D. Mandal, P.R. Gogate, A. Ghosh, R.L. Bhardwaj   +4 more
doaj   +1 more source

Improvement of Dissolution Test Using Microdialysis Method

YAKUGAKU ZASSHI, 2009
Dissolution testing is a core performance test in pharmaceutical development and quality control. Generally, the HPLC method uses the analysis of dissolution testing. In this study, we attempted to improve the dissolution test by using microdialysis methods. We also investigated the comparison of the conventional HPLC dissolution method (batch-sampling
Noriaki, Nagai, Takatoshi, Murao, Yoshimasa, Ito   +2 more
openaire   +3 more sources