Results 31 to 40 of about 56,903 (208)
The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000 [PDF]
Advanced Pharmaceutical Bulletin, 2015 Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion.
Jafar Akbari +6 more
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Improvement of Dissolution Test Using Microdialysis Method
YAKUGAKU ZASSHI, 2009 Dissolution testing is a core performance test in pharmaceutical development and quality control. Generally, the HPLC method uses the analysis of dissolution testing. In this study, we attempted to improve the dissolution test by using microdialysis methods. We also investigated the comparison of the conventional HPLC dissolution method (batch-sampling
Noriaki, Nagai +2 more
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Improving Riparin-A Dissolution through a Laponite Based Nanohybrid
Pharmaceutics, 2023 (1) Background: Riparin-A presents several pharmacological activities already elucidated, such as antimicrobial modulator, antileishmania, anxiolytic, anti-inflammatory, antinociceptive, and antioxidant. Even with important bioactive effects, the applicability of Riparin-A is limited due to its low solubility in water, impairing its dissolution in ...
Duanne Mendes Gomes +7 more
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Pharmaceutics, 2022 Estimating the dissolution behavior of a solid in the nasal mucus is challenging for solid dosage forms designed for the nasal application as the solid dissolves into nasal mucus and permeates through the mucosa.
Daisuke Inoue +2 more
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PharmaceuticsBackground/Objectives: Selective laser sintering (SLS) is one of the most promising 3D printing techniques for pharmaceutical applications as it offers numerous advantages, such as suitability to work with already approved pharmaceutical excipients, the ...
Nikola Pešić +5 more
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Iraqi Journal of Pharmaceutical Sciences, 2022 Risperidone is an atypical antipsychotic drug that is used for treating schizophrenia, bipolar mania, and autism. Risperidone rebalances dopamine and serotonin to improve thinking, mood, and behavior by working on dopamine and serotonin α2receptor ...
Hayder Emad, Shaimaa Nazar Abd-Alhammid
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Biology, Medicine & Natural Product ChemistryPoor aqueous solubility limits the bioavailability of non-steroidal anti-inflammatory drugs like mefenamic acid. This study aims to improve the solubility and dissolution of mefenamic acid through crystalline solid dispersions using solvent evaporation ...
Indra Indra +5 more
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Improved dissolution of oleanolic acid with ternary solid dispersions [PDF]
AAPS PharmSciTech, 2007 The purpose of this study was to enhance the dissolution of oleanolic acid by solid dispersions consisting of the drug, a polymeric carrier, and a surfactant. Binary solid dispersions consisting of oleanolic acid and polyvinylpyrrolidone were prepared for comparison.
Longxiao, Liu, Xiaocui, Wang
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Using fluid bed granulation to improve the dissolution of poorly water-soluble drugs
Brazilian Archives of Biology and Technology, 2012 In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and croscarmellose sodium and then ...
Andrea Ikeda Takahashi +4 more
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Improvement of firocoxib dissolution performance through electrospun fibers obtained from different polymer/surfactant associations [PDF]
, 2019 An electrospinning process was optimized to produce fibers of micrometric size with dierent combinations of polymeric and surfactant materials to promote the dissolution rate of an insoluble drug: firocoxib.
Mirena Sakaj +6 more
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