Results 21 to 30 of about 56,903 (208)
Pharmaceutics, 2022 Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence.
Francesca Maestrelli +4 more
doaj +1 more source
Surface dissolution UV imaging for characterization of superdisintegrants and their impact on drug dissolution [PDF]
, 2020 Superdisintegrants are a key excipient used in immediate release formulations to promote fast tablet disintegration, therefore understanding the impact of superdisintegrant variability on product performance is important.
Fotaki, N. +4 more
core +1 more source
Improved Formazan Dissolution for Bacterial MTT Assay
Microbiology Spectrum, 2021 Reduction of the water-soluble tetrazolium salt 3-(4,5-dimethylthiazol)-2,5 diphenyl-tetrazolium bromide (MTT) to purple, water-insoluble formazan is commonly used for assessment of cell viability and proliferation. Spectrophotometric detection of formazan requires its solubilization.
openaire +4 more sources
Nanotechnology Versus other Techniques in Improving Drug Dissolution [PDF]
Current Pharmaceutical Design, 2014 Many newly discovered drug molecules have low aqueous solubility, which results in low bioavailability. One way to improve their dissolution is to formulate them as nanoparticles, which have high specific surface areas, consequently increasing the dissolution rate and solubility. Nanoparticles can be produced via top-down or bottom-up methods. Top-down
Kwok, PCL, Chan, HK
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Acta Pharmaceutica, 2016 The dissolution rate of anhydrous acyclovir was improved by the preparation of physical mixtures and solid dispersions with the non-ionic polymer Pluronic F127 using the kneading method at different drug-to-polymer ratios.
Karolewicz Bożena +3 more
doaj +1 more source
Pharmaceuticals, 2023 In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan ...
Manami Dhibar +7 more
doaj +1 more source
Improvement of Dissolution Properties of Etoricoxib through Solid Dispersion Technique
, 2022 : Etoricoxib, a non-steroidal anti-inflammatory drug, is used to Osteoarthritis, Rheumatoid arthritis and Acute Gouty arthritis. Etoricoxib is practically insoluble in water; hence present study was carried out to enhance dissolution properties of ...
Taneeru Venkata Narayana +3 more
core +1 more source
, 2022 The present study aimed to develop an oily suspension of micronized crystalline lutein (LT) for the improvement of dissolution and oral absorption properties.
Tetsuya Matsushita +11 more
core +1 more source
Improvement of dissolution rate of indomethacin by inkjet printing
European Journal of Pharmaceutical Sciences, 2015 The aim of this study was to prepare printable inks of the poorly water soluble drug indomethacin (IMC), fabricate printed systems with flexible doses and investigate the effect of ink excipients on the printability, dissolution rate and the solid state properties of the drug.
Henrika, Wickström +12 more
openaire +3 more sources
Preparation and characterization of domperidone nanoparticles for dissolution improvement
Iraqi Journal of Pharmaceutical Sciences, 2018 This study was carried out to prepare and characterize domperidone nanoparticles to enhance solubility and the release rate. Domperidone is practically insoluble in water and has low and an erratic bioavailability range from 13%-17%.
Mohammed Sabar Al-lami +2 more
doaj +1 more source