Results 1 to 10 of about 52,860 (118)

Mechanism and mitigation of stainless steel dissolution in LiFSI-based lithium-ion battery electrolytes [PDF]

Nature Communications
Lithium bis(fluorosulfonyl)imide has emerged as a promising alternative to lithium hexafluorophosphate as conducting salt in battery electrolytes due to its favorable physicochemical properties.
Peng Yan, Marian Cristian Stan, Kazem Zhour, Diddo Diddens, Christian Wölke, Rayan Guerdelli, Martin Winter, Isidora Cekic-Laskovic   +7 more
doaj   +2 more sources

Preformulation Studies of Ezetimibe-Simvastatin Solid Dispersions in the Development of Fixed-Dose Combinations

Pharmaceutics, 2022
Two active pharmaceutical ingredients (APIs) with limited solubility, simvastatin and ezetimibe, prepared as a drug-drug solid dispersion (SD) was evaluated for physicochemical, microstructural, and aqueous dissolution properties.
Agata Górniak, Adrianna Złocińska, Mateusz Trojan, Adrianna Pęcak, Bożena Karolewicz   +4 more
doaj   +1 more source

Screening of Fenofibrate-Simvastatin Solid Dispersions in the Development of Fixed-Dose Formulations for the Treatment of Lipid Disorders

Pharmaceutics, 2023
The combination of statins and fibrates in the treatment of lipid abnormalities effectively regulates individual lipid fraction levels. In this study, the screening and assessment of the physicochemical properties of simvastatin-fenofibrate solid ...
Agata Górniak, Hanna Czapor-Irzabek, Adrianna Złocińska, Agnieszka Gawin-Mikołajewicz, Bożena Karolewicz   +4 more
doaj   +1 more source

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach

Pharmaceuticals, 2022
The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such ...
Nawaf Almotairi, Gamal M. Mahrous, Saleh Al-suwayeh, Mohsin Kazi   +3 more
doaj   +1 more source

Development and Characterization of Liquisolid Tablets Based on Mesoporous Clays or Silicas for Improving Glyburide Dissolution

Pharmaceutics, 2020
The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets based on a liquisolid approach.
Marzia Cirri, Paola Mura, Maurizio Valleri, Letizia Brunetti   +3 more
doaj   +1 more source

IMPROVEMENT OF DISSOLUTION BEHAVIOR OF TEMAZEPAM [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1991
The interaction between temazepam and b-cyclodextrin (b-CD) or hydroxypropyl b-cyclodextrin (HPb-CD) was studied in aqueous solution. The attempts made to obtain temazepam-cyclodextrin complexes in the solid state through freeze drying or slow ...
J. Aiache, S. Ahmed, S. Saleh
doaj   +1 more source

Pharmaceutical co-crystals of posaconazole for improvement of physicochemical properties [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
Posaconazole exerts an extended spectrum of antifungal activity against various strains of clinically relevant moulds and yeasts. In recent years, antifungal triazole posaconazole has become increasingly important for the prophylaxis and treatment of ...
Monika Nijhawan, Monika Godugu, Trapti Saxena, Talat Farheen, Kanchan Dwivedi   +4 more
doaj   +1 more source

Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine

Molecules, 2020
Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by ...
Mohsin Kazi, Ahmad A. Shahba, Saad Alrashoud, Majed Alwadei, Abdelrahman Y. Sherif, Fars K. Alanazi   +5 more
doaj   +1 more source

Cellulose Dissolution in Ionic Liquid under Mild Conditions: Effect of Hydrolysis and Temperature

Fibers, 2021
This study investigated the effect of acid hydrolysis of cellulose on its dissolution under mild conditions in ionic liquid, 1-butyl-3-methylimidazolium acetate/N,N-dimethylacetamide (BMIMAc/DMAc).
Sanjit Acharya, Yang Hu, Noureddine Abidi   +2 more
doaj   +1 more source

EFFECT OF BLOCK COPOLYMERS ON THE DISSOLUTION OF SOME WATER-INSOLUBLE DRUGS: 1. NIFEDIPINE-PLURONIC F-127 SOLID DISPERSION SYSTEM [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1994
The effect of pluronic F-127, a block copolymer, on enhancing the dissolution rate of water-insoluble drugs was studied. Solid dispersions of nifedipine, a model water-insoluble drug, with pluronic F-127 and PVP at different drug : polymer ratios were ...
Sayed Khidr
doaj   +1 more source