Preparation And Characterization Of Nimesulide Nanoparticles For Dissolution Improvement
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018 Nimesulide is one of the types of non-steroidal anti-inflammatory drugs, widely used as analgesic and antipyretic. It is classified as class II drugs according to BCS guidance because of low solubility in water that leads to decrease in dissolution rate.
Inas F. Abd-AlRazaq +2 more
doaj +3 more sources
Role of Solvents in Improvement of Dissolution Rate of Drugs: Crystal Habit and Crystal Agglomeration [PDF]
Advanced Pharmaceutical Bulletin, 2015 Crystallization is often used for manufacturing drug substances. Advances of crystallization have achieved control over drug identity and purity, but control over the physical form remains poor.
Maryam Maghsoodi
doaj +2 more sources
Improvement of Solubility and Dissolution of Niclosamide using Metal Organic Framework 5 (MOF-5)
Iraqi Journal of Pharmaceutical SciencesMetal-organic frameworks-5 (MOF-5) were explored for enhancement of the solubility and dissolution of the drug niclosamide (NIC). MOF-5 was synthesized by solvothermal method and NIC was loaded into it (NIC@MOF-5).
Hayder Yahya Mansoor Al-Jarsha +1 more
doaj +3 more sources
Influence of the Efavirenz Micronization on Tableting and Dissolution
Pharmaceutics, 2012 The purpose of this study was to propose an analytical procedure that provides the effects of particle size and surface area on dissolution of efavirenz.
Lucio Mendes Cabral +9 more
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Liquisolid Systems to Improve the Dissolution of Furosemide [PDF]
Scientia Pharmaceutica, 2010 A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro dissolution properties of the practically water insoluble loop diuretic furosemide, by utilising liquisolid ...
Akinlade, Babatunde +3 more
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Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals [PDF]
Molecules, 2020 Both rosiglitazone and metformin have effects on blood glucose regulation and the proliferation of liver cancer cells. Combination therapy with these two drugs is common and effective for the treatment of diabetes in the clinic, however, the application of these two drugs is influenced by the poor dissolution of rosiglitazone and the gastrointestinal ...
Xufei Bian +7 more
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Isostructural cocrystals of metaxalone with improved dissolution characteristics
RSC Advances, 2021 Metaxalone forms isostructural cocrystals with nicotinamide and salicylamide that offer a solubility advantage compared to the native drug. A drug–drug homosynthon is retained in all the cocrystal structures.
Sunil Kumar Gohel +5 more
openaire +3 more sources
Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine) [PDF]
, 2007 Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica.
Yousef Javadzadeh +8 more
core +1 more source
SOLUBILITY AND DISSOLUTION ENHANCEMENT OF KETOTIFEN BY SOLID DISPERSION TECHNIQUE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2015 Ketotifen (KT) solid dispersions and physical mixtures were prepared with the objective of solubility and dissolution improvement using Hydroxypropyl-Beta-Cyclodextrin (HP-β-CD), Pluronic 127 (PF-127), Pluronic 68 (PF-68), Polyethylene glycol 6000 (PEG ...
Omnia Mahmoud +2 more
doaj +1 more source
Polytechnic Journal, 2021 Drugs which fall into Class II of Biopharmaceutical Classification System suffer from poor aqueous solubility that limits the dissolution and oral bioavailability.
Hemn L. Qader +2 more
doaj +1 more source