Results 11 to 20 of about 261,203 (312)

Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine

open access: yesMolecules, 2020
Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by ...
Mohsin Kazi   +5 more
doaj   +1 more source

Dissolution Enhancement of Meloxicam Tablets from the Synergistic Effect of Hydrotropic and Sublimating Agent

open access: yesPolytechnic Journal, 2021
Drugs which fall into Class II of Biopharmaceutical Classification System suffer from poor aqueous solubility that limits the dissolution and oral bioavailability.
Hemn L. Qader   +2 more
doaj   +1 more source

Isostructural cocrystals of metaxalone with improved dissolution characteristics

open access: yesRSC Advances, 2021
Metaxalone forms isostructural cocrystals with nicotinamide and salicylamide that offer a solubility advantage compared to the native drug. A drug–drug homosynthon is retained in all the cocrystal structures.
Sunil Kumar Gohel   +5 more
openaire   +3 more sources

Role of Cyclodextrins and Drug Solid State Properties on Flufenamic Acid Dissolution Performance from Tablets

open access: yesPharmaceutics, 2022
Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence.
Francesca Maestrelli   +4 more
doaj   +1 more source

Liquisolid Systems to Improve the Dissolution of Furosemide [PDF]

open access: yesScientia Pharmaceutica, 2010
A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro dissolution properties of the practically water insoluble loop diuretic furosemide, by utilising liquisolid ...
Akinlade, Babatunde   +3 more
openaire   +3 more sources

Dissolution improvement of high drug-loaded solid dispersion [PDF]

open access: yesAAPS PharmSciTech, 2006
This study focused on an investigation of a high drug-loaded solid dispersion system consisting of drug, carrier, and surfactant. Solid dispersions of a water-insoluble ofloxacin (OFX) with polyethylene glycol (PEG) of different molecular weights, namely binary solid dispersion systems, were prepared at drug to carrier not less than 5:5. Polysorbate 80,
Siriporn, Okonogi   +1 more
openaire   +2 more sources

Chemo-mechanical modeling of artificially and naturally bonded soils [PDF]

open access: yes, 2019
Chemo-mechanical effects are known to be significant in a number of applications in modern geomechanics, ranging from slope stability assessment to soil improvement and CO2 sequestration.
Cecinato, Francesco   +2 more
core   +2 more sources

A Systems Thinking Approach to Redesigning the Patient Experience to Reduce 30 Day Hospital Readmission [PDF]

open access: yes, 2018
INTRODUCTION The cost of medical care is spiraling out of control, and one of the many reasons is lack of preventative care, poor communication to the patient and primary caregiver(s) both in an inpatient and outpatient setting.
DePrince, RN, BA, CCRN, SCRN, Maureen   +6 more
core   +2 more sources

Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment

open access: yesPharmaceuticals, 2023
In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan ...
Manami Dhibar   +7 more
doaj   +1 more source

Analysis of possibilities to increase oil recovery with the use of nitrogen in the context of deep oil deposits of the Dnipro-Donetsk oil-and-gas Ukrainian province [PDF]

open access: yes, 2019
Purpose is to increase oil recovery of deep oil deposits of the Dnipro-Donetsk oil-and-gas Ukrainian province with the use of nitrogen. Methods. Experiments, intended to residual oil displacement with the use of different driving agents, involved ...
Kondrat, O, Lukin, O, Smolovyk, L
core   +2 more sources

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