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A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source

Electrospun core-shell nanofibres embedding drug nanocrystals for long-acting mucosal delivery. [PDF]

open access: yesMater Today Bio
Zucca G   +8 more
europepmc   +1 more source

Changes in perceived psychosocial working conditions after psychotherapeutic consultation at work - exploratory post-hoc analyses from a randomized controlled trial. [PDF]

open access: yesBMC Public Health
Weber J   +10 more
europepmc   +1 more source
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Dissolution and Dissolution Test Apparatus: A Review

Asian Journal of Research in Pharmaceutical Sciences, 2021
Dissolution is an official test. These used by pharmacopeias for evaluating drug release of solid and semisolid dosages forms. The application of the dissolution testing ensures consistent product quality and to predict in vivo drug bioavailability.
Priyanka M. Salve   +3 more
openaire   +1 more source

Dissolution Testing of Nitroglycerin Tablets

Journal of Pharmaceutical Sciences, 1976
The available types of dissolution testing apparatus for tablets and capsules are inapplicable to sublingual tablets, since these tablets are formulated to release their drug content within minutes in a small volume of fluid. A simple dissolution test method was developed for nitroglycerin tablets based on the reduction of nitroglycerin at a rotating ...
C A, Gaglia   +3 more
openaire   +2 more sources

Calorimetric dissolution testing.

Drug Development and Industrial Pharmacy, 1991
AbstractIt is frequently desirable to obtain dissolution information about a new drug in the pre-formulation stage. This is difficult for two reasons. One is that there usually is not much drug available at this particular point in time (and e.g. a rotation disk dissolution (Levich, 1962) can hence, not be carried out). Another reason is that the assay
K. Iba   +3 more
openaire   +1 more source

Dynamic Dissolution: A Step Closer to Predictive Dissolution Testing?

Molecular Pharmaceutics, 2010
The use of compendial dissolution techniques to characterize the performance of oral drug delivery systems is an established area of pharmaceutical science. However, compendial equipment is recognized as being limited in its ability to replicate the dynamic aspects of in vivo dissolution that are associated with dosage form transit through a rapidly ...
openaire   +2 more sources

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