Results 251 to 260 of about 136,291 (302)

Dissolution Apparatus with Multiple Testing Stations

Journal of Pharmaceutical Sciences, 1968
An apparatus in which 20 dissolution tests may be conducted simultaneously is described. A single set of controls maintains the test conditions in all 20 dissolution vessels. Provisions have been made to sample automatically and simultaneously from each vessel at predetermined time intervals.
R A, Castello, G, Jellinek, J M, Konieczny, K C, Kwan, R O, Toberman   +4 more
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Dissolution testing of amorphous solid dispersions

International Journal of Pharmaceutics, 2013
The main purpose of this study was to investigate the effect of different polymers, with varying physicochemical properties and molecular weight on the stability and dissolution of co-milled amorphous solid dispersions (ASDs) of piroxicam (PRX). The stability of amorphous PRX (aPRX) in ASDs was significantly improved by the polymers.
K, Kogermann, A, Penkina, K, Predbannikova, K, Jeeger, P, Veski, J, Rantanen, K, Naelapää   +6 more
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Dissolution Test for Silymarin Tablets and Capsules

Drug Development and Industrial Pharmacy, 2001
Silybine (SBN), isosilybine (ISBN), silycristine (SCN), silydianine (SDN), and taxifoline (TXF) are the main active flavonoids commonly found in the dried fruits of Silybum marianum, Gaertner (Compositae). Concentrations of these compounds, except TXF, are usually expressed together as silymarin content.
A, Campodónico, E, Collado, R, Ricci, H, Pappa, A, Segall, M T, Pizzorno   +5 more
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New In Vitro Dissolution Test Apparatus

Journal of Pharmaceutical Sciences, 1979
A new in vitro dissolution test apparatus was designed and evaluated. Compressed tablets of drugs representing different solubility characteristics were tested at various air pressures and compared to dissolution patterns of similar tablets by the Levy beaker and USP methods.
S S, Nasir, L O, Wilken, S M, Nasir
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A critical analysis of a capsule dissolution test

Journal of Pharmaceutical Sciences, 1969
A suitably modified USP disintegration apparatus has been used to obtain dissolution rate data for chloramphenicol capsules. Differences between various commercial and laboratory formulations of this drug were reflected in their dissolution profiles. Several shortcomings of this apparatus are described.
R J, Withey, C A, Mainville
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Pharmaceutical Dissolution Testing

2005
Historical Development of Dissolution Testing. Compendial Testing Equipment: Calibration, Qualification, and Sources of Error. Compendial Requirements of Dissolution Testing. The Role of Dissolution Testing in the Regulation of Pharmaceuticals: The FDA Perspective.
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Dissolution Testing

Dissolution testing measures the rate and extent of drug release from pharmaceutical dosage forms. USP apparatus types 1-7 simulate in-vivo conditions with specific designs for various dosage forms, each requiring proper calibration and qualification.
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An Exploration of Dissolution Tests for Inhalation Aerosols

AAPS PharmSciTech
This study aimed to establish a feasible dissolution method for inhalation aerosols. A method of collecting fine particles was investigated to capture aerosol particles less than 4 μm in diameter for dissolution tests. This dose collection method enabled the aerosol particles to be uniformly distributed on the glass fiber filter, thus considerably ...
Min Wang, Zhaoying Fang, Kunhao Yang, Xiaowei Guo, Shangyang Li, Ali Liu   +5 more
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4 Dissolution Testing

2008
Dissolution can be defined as a process by which the drug substance in a formulation dissolves into solution. Although dissolution appears to be a simple process, developing a suitable dissolution test requires careful considerations of the physicochemical properties of the drug substance, excipients, dosage form designs, dissolution media, and other ...
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Handbook of Dissolution Testing

Over 20 years ago the Third Edition of the Handbook of Dissolution Testing was published. During that time to the present, new regulatory expectations, new compendial chapters and guidances, new equipment especially for special dosage forms, and more meaningful dissolution test media and conditions have significantly influenced every aspect of ...
Crist Bryan, Gray Vivian, Hanson Royal
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