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Prolonged release starch acetate matrix tablets relationships between formulation properties and in vitro dissolution behaviour [PDF]
Pajander, Jari
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Dissolution and Dissolution Test Apparatus: A Review
Asian Journal of Research in Pharmaceutical Sciences, 2021Dissolution is an official test. These used by pharmacopeias for evaluating drug release of solid and semisolid dosages forms. The application of the dissolution testing ensures consistent product quality and to predict in vivo drug bioavailability.
Priyanka M. Salve +3 more
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Dissolution Testing of Nitroglycerin Tablets
Journal of Pharmaceutical Sciences, 1976The available types of dissolution testing apparatus for tablets and capsules are inapplicable to sublingual tablets, since these tablets are formulated to release their drug content within minutes in a small volume of fluid. A simple dissolution test method was developed for nitroglycerin tablets based on the reduction of nitroglycerin at a rotating ...
C A, Gaglia +3 more
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Calorimetric dissolution testing.
Drug Development and Industrial Pharmacy, 1991AbstractIt is frequently desirable to obtain dissolution information about a new drug in the pre-formulation stage. This is difficult for two reasons. One is that there usually is not much drug available at this particular point in time (and e.g. a rotation disk dissolution (Levich, 1962) can hence, not be carried out). Another reason is that the assay
K. Iba +3 more
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Dynamic Dissolution: A Step Closer to Predictive Dissolution Testing?
Molecular Pharmaceutics, 2010The use of compendial dissolution techniques to characterize the performance of oral drug delivery systems is an established area of pharmaceutical science. However, compendial equipment is recognized as being limited in its ability to replicate the dynamic aspects of in vivo dissolution that are associated with dosage form transit through a rapidly ...
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Phosphate buffer interferes dissolution of prazosin hydrochloride in compendial dissolution testing
Drug Metabolism and Pharmacokinetics, 2023The purpose of this study was to elucidate the lack of supersaturation behavior in the dissolution profile of prazosin hydrochloride (PRZ-HCl) in the compendial dissolution test. The equilibrium solubility was measured by a shake-flask method. Dissolution tests were performed by a compendial paddle method with a phosphate buffer solution (pH 6.8, 50 mM
Hiroshi, Sudaki +3 more
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Dissolution test for citalopram in tablets and comparison of in vitro dissolution profiles
European Journal of Pharmaceutics and Biopharmaceutics, 2007A dissolution test for tablets containing 20 mg of citalopram was developed and validated using a reverse-phase liquid chromatographic method and this dissolution test was applied to compare dissolution profiles. The sink conditions, filters, stability of the drug and specificity on different dissolution media were tested to choose a discriminatory ...
Júlia, Menegola +2 more
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Dissolution test acceptance sampling plans
Journal of Biopharmaceutical Statistics, 1995The U.S. Pharmacopeia (USP) general monograph provides a standard for dissolution compliance with the requirements as stated in the individual USP monograph for a tablet or capsule dosage form. The acceptance rules recommended by USP have important roles in the quality control process.
Y, Tsong +3 more
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