Results 241 to 250 of about 6,915,672 (299)

Dissolution test for citalopram in tablets and comparison of in vitro dissolution profiles

European Journal of Pharmaceutics and Biopharmaceutics, 2007
A dissolution test for tablets containing 20 mg of citalopram was developed and validated using a reverse-phase liquid chromatographic method and this dissolution test was applied to compare dissolution profiles. The sink conditions, filters, stability of the drug and specificity on different dissolution media were tested to choose a discriminatory ...
Júlia, Menegola, Martin, Steppe, Elfrides E S, Schapoval   +2 more
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Dissolution Apparatus with Multiple Testing Stations

Journal of Pharmaceutical Sciences, 1968
An apparatus in which 20 dissolution tests may be conducted simultaneously is described. A single set of controls maintains the test conditions in all 20 dissolution vessels. Provisions have been made to sample automatically and simultaneously from each vessel at predetermined time intervals.
R A, Castello, G, Jellinek, J M, Konieczny, K C, Kwan, R O, Toberman   +4 more
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Dissolution test acceptance sampling plans

Journal of Biopharmaceutical Statistics, 1995
The U.S. Pharmacopeia (USP) general monograph provides a standard for dissolution compliance with the requirements as stated in the individual USP monograph for a tablet or capsule dosage form. The acceptance rules recommended by USP have important roles in the quality control process.
Y, Tsong, T, Hammerstrom, K, Lin, T E, Ong   +3 more
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Dissolution testing of amorphous solid dispersions

International Journal of Pharmaceutics, 2013
The main purpose of this study was to investigate the effect of different polymers, with varying physicochemical properties and molecular weight on the stability and dissolution of co-milled amorphous solid dispersions (ASDs) of piroxicam (PRX). The stability of amorphous PRX (aPRX) in ASDs was significantly improved by the polymers.
K, Kogermann, A, Penkina, K, Predbannikova, K, Jeeger, P, Veski, J, Rantanen, K, Naelapää   +6 more
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Pharmaceutical Dissolution Testing

2005
Historical Development of Dissolution Testing. Compendial Testing Equipment: Calibration, Qualification, and Sources of Error. Compendial Requirements of Dissolution Testing. The Role of Dissolution Testing in the Regulation of Pharmaceuticals: The FDA Perspective.
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Dissolution Test for Silymarin Tablets and Capsules

Drug Development and Industrial Pharmacy, 2001
Silybine (SBN), isosilybine (ISBN), silycristine (SCN), silydianine (SDN), and taxifoline (TXF) are the main active flavonoids commonly found in the dried fruits of Silybum marianum, Gaertner (Compositae). Concentrations of these compounds, except TXF, are usually expressed together as silymarin content.
A, Campodónico, E, Collado, R, Ricci, H, Pappa, A, Segall, M T, Pizzorno   +5 more
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New In Vitro Dissolution Test Apparatus

Journal of Pharmaceutical Sciences, 1979
A new in vitro dissolution test apparatus was designed and evaluated. Compressed tablets of drugs representing different solubility characteristics were tested at various air pressures and compared to dissolution patterns of similar tablets by the Levy beaker and USP methods.
S S, Nasir, L O, Wilken, S M, Nasir
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A critical analysis of a capsule dissolution test

Journal of Pharmaceutical Sciences, 1969
A suitably modified USP disintegration apparatus has been used to obtain dissolution rate data for chloramphenicol capsules. Differences between various commercial and laboratory formulations of this drug were reflected in their dissolution profiles. Several shortcomings of this apparatus are described.
R J, Withey, C A, Mainville
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Dissolution Testing

Dissolution testing measures the rate and extent of drug release from pharmaceutical dosage forms. USP apparatus types 1-7 simulate in-vivo conditions with specific designs for various dosage forms, each requiring proper calibration and qualification.
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4 Dissolution Testing

2008
Dissolution can be defined as a process by which the drug substance in a formulation dissolves into solution. Although dissolution appears to be a simple process, developing a suitable dissolution test requires careful considerations of the physicochemical properties of the drug substance, excipients, dosage form designs, dissolution media, and other ...
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