Results 111 to 120 of about 2,316 (200)

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, Volume 13, Issue 43, 3 August 2026.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Deep Learning Prediction of Surface Roughness in Multi‐Stage Microneedle Fabrication: A Long Short‐Term Memory‐Recurrent Neural Network Approach

Advanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
A sequential deep learning framework is developed to model surface roughness progression in multi‐stage microneedle fabrication. Using real‐world experimental data from 3D printing, molding, and casting stages, an long short‐term memory‐based recurrent neural network captures the cumulative influence of geometric parameters and intermediate outputs ...
Abdollah Ahmadpour, Sara Soltanabadi Farshi, Tuanna Ozcan, Amir Mohammad Ketabchi, Alper Kiraz, Savas Tasoglu   +5 more
wiley   +1 more source

Bone Marrow Stem Cell Exosomes Protect Lung Cells from Oxygen Damage by Regulating miR‐23a‐3p/Slc7a2 Pathway

The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
Exosomal miR‐23a‐3p from BMSCs directly targets Slc7a2 mRNA. By repressing Slc7a2, miR‐23a‐3p suppresses hyperoxia‐triggered apoptosis, facilitates proliferation and reduces ROS production in AECIIs in vitro. The miR‐23a‐3p/Slc7a2 axis modulates numerous biochemical markers in AECII supernatant and neonatal rat serum under hyperoxia (P 〈 0.05 ...
Qifei He, Huaiwu Zheng, Junhao Xiong, Wei Yang   +3 more
wiley   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

Advances in Smart Wearable Biosensors for Non‐Invasive and Microneedle‐Based Health Monitoring: A Physiological Fluids‐Based Approach

Small Structures, Volume 7, Issue 8, August 2026.
This review highlights recent advancements in smart wearable biosensors for non‐invasive, microneedle‐based health monitoring via physiological fluids. It focuses on functional materials, biomarker detection strategies, sensor integration and validation methods.
Shuva Bhowmik, Azam Ali
wiley   +1 more source

Assessing insulin stability in dissolving microneedles

Health Engineering
The proper storage temperature of dissolving insulin microneedles (INS MNs) is crucial for their clinical application to prevent insulin inactivation. This study aims to explore the impact of temperature on the dissolving INS MNs and offer appropriate storage recommendations.
Zhang, Xiao Peng, Jing, Li Yue, Feng, Yun Hao, Jiao, Jie, Li, Zhuo Lin, Yu, Bin Bin, Yu, Ruixing, Chen, Bo Zhi, Shahbazi, Mohammad-Ali, Guo, Xin Dong   +9 more
openaire   +1 more source

Prevention of HBV Mother‐To‐Child Transmission (MTCT) Using Targeted HBV Birth Dose, and Treatment of High Viral Load Pregnant Women in Uganda

Journal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Hepatitis B virus (HBV) mother‐to‐child transmission (MTCT) remains a major challenge in Uganda, where 43% of births occur at home, and access to timely birth dose (BD) vaccination is limited. We evaluated the impact of combining universal three‐dose (3D) infant vaccination, targeted BD vaccination, and maternal antiviral treatment for high ...
Samantha Hall, Ponsiano Ocama, Danielle Leavelle, Julius Kiwanuka, Brian Lwanga, Joan Nankya‐Mutyoba, Calvin Q. Pan, Christine Namulindwa, Viola Kasone, Rachel Beyagira, Homie Razavi   +10 more
wiley   +1 more source

Technical challenges and quality considerations for dissolving microneedles. [PDF]

Int J Pharm
Kamal NS, Acheampong S, Zaman RU, Strasinger C, Clark AG, Zhu A, Tang Y, Zidan A, Ashraf M.   +8 more
europepmc   +1 more source

Development and Optimization of Polymer-Based Dissolving Microneedles Fabricated by Mold Casting Method. [PDF]

Polymers (Basel)
Bodnar L, Kovalova T, Yakovenko V, Koshovyi O, Georgiev KD, Slavov IZ, Vyshnevska L.   +6 more
europepmc   +1 more source