Results 71 to 80 of about 8,450,223 (267)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Learners and E-Tutors Experiences of Authentic Assessment in Babcock University Centre for Open Distance and e-Learning

open access: yesWest African Journal of Open and Flexible Learning, 2022
Authentic Assessment (AA) has been heralded as the form of assessment that reflects the real world in classroom learning. Recognising this, the Commonwealth of Learning (COL), in collaboration with the National Universities Commission (NUC) in Nigeria ...
Mobolanle Ebunoluwa Sotunsa   +4 more
doaj  

From a Distance [PDF]

open access: yes, 2012
An exhibition of very large scale documentary photographs of the Elephant and Castle exhibited at London College of Communication. From a Distance was a commission given to photographer Paul Reas to respond to the regeneration of the Elephant and Castle ...
Reas, Paul   +2 more
core  

Distance Estimation in Cosmology

open access: yes, 1995
In this paper we outline the framework of mathematical statistics with which one may study the properties of galaxy distance estimators. We describe, within this framework, how one may formulate the problem of distance estimation as a Bayesian inference ...
Bertschinger   +76 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Relativistic Distance

open access: yes, 2003
In this paper, we prove that two different observers don't equally measure the distance between two points A and B. For this, we introduce some postulates and obtain a new formula to show distance between A and B. In this formula, radius of universe, n, is entered such that if n tends to infinity the ordinary distance is obtained.
Akbari, M., Darvishi, M. T.
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Distance measures in cosmology [PDF]

open access: yes, 1999
Formulae for the line-of-sight and transverse comoving distances, proper motion distance, angular diameter distance, luminosity distance, k-correction, distance modulus, comoving volume, lookback time, age, and object intersection probability are all ...
Hogg, David W.
core   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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