Results 71 to 80 of about 4,557,374 (284)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

The world of learning

open access: yesJournal of Open, Flexible and Distance Learning, 2012
Column about conferences events and new publications in distance learning.
Glenise Dreaver, Terry Hearn
doaj   +2 more sources

Learning domain invariant representations by joint Wasserstein distance minimization

open access: hybrid, 2023
Léo Andéol   +5 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Authenticity of Ficus Hispida as a Local Traditional Product in the Lembah Lenggong World Heritage Site

open access: yesSHS Web of Conferences, 2014
Lembah Lenggong is a place well known amongst locals as an archaeological site; the valley has been attested as a World Heritage Site. There is an overwhelming variety of plant species that are uniquely used in their cultural and traditional cuisines ...
Abd Aziz Siti Hajar   +2 more
doaj   +1 more source

Homogeneous Velocity‐Distance Data for Peculiar Velocity Analysis. III. The Mark III Catalog of Galaxy Peculiar Velocities [PDF]

open access: green, 1997
Jeffrey A. Willick   +5 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Open and Innovative Schooling: An Implementation Experience in Fifteen Secondary Schools across Mozambique

open access: yesJournal of Learning for Development, 2021
This case study explores the open and innovative schooling model piloted in fifteen secondary schools across all regions of Mozambique in the period 2018 to 2020.
Sérgio Paulo Cossa   +2 more
doaj  

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