Results 81 to 90 of about 8,524,151 (285)

p-Skwarczyński distance

Complex Analysis and its Synergies, 2023
We introduce a new distance on a domain $Ω\subset \mathbb{C}^n$ using the `minimizer' functions on $A^p(Ω)$. We discuss its invariance, completeness, and other aspects related to it.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Online professional development conferences: An effective, economical and eco-friendly option

Canadian Journal of Learning and Technology, 2010
In order to stay current within their field, many professionals regularly attend conferences and training events in distant locales. Travel to these conferences costs professionals, and their sponsor organizations, both time and money.
Lynn Anderson, Terry Anderson
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Distance Estimation in Cosmology

, 1995
In this paper we outline the framework of mathematical statistics with which one may study the properties of galaxy distance estimators. We describe, within this framework, how one may formulate the problem of distance estimation as a Bayesian inference ...
Bertschinger, Chamcham, Dekel, Dekel, Dekel, Dressler, Dressler, Eastman, Eddington, Faber, Feast, Federspiel, Fiegelson, Fisher, Freedman, Freudling, Giraud, Gould, Hamuy, Heavens, Hendry, Hendry, Hendry, Hendry, Hendry, Hoel, Hogg, Hudson, Hudson, J.F.L. Simmons, Jacoby, Kanbur, Kendall, Kirschner, Lahav, Landy, Lauer, Lynden-Bell, M.A. Hendry, Malmquist, Malmquist, Mathewson, Mood, Mould, Newsam, Newsam, Nusser, Pierce, Pierce, Rauzy, Riess, Riess, Rubin, Saha, Saha, Salucci, Sandage, Sandage, Sandage, Sandage, Schechter, Schmidt, Schmidt, Shaya, Shaya, Simmons, Sodré, Teerikorpi, Tonry, Triay, Tully, van den Bergh, Vaughan, Visvanathan, von Mises, Willick, Zaccheo   +76 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

An Appropriateness of Primary School Teachers’ Pedagogical Skills for Teaching The 2023 Curriculum in Chongwe District, Zambia

Journal of Arts, Humanities and Social Science
The study sought to describe the appropriateness of primary school teachers’ pedagogical skills for teaching the 2023 curriculum in Chongwe District.
Pamela Kabwali, James Mwale, Simeon Mbewe, Simui Francis   +3 more
doaj   +1 more source

Factors Affecting the Participation of the Deaf and Hard of Hearing in e-Learning and Their Satisfaction: A Quantitative Study

International Review of Research in Open and Distributed Learning, 2017
Today the digital divide is measured not so much by access to the internet but by people's ability to interact in cyberspace, which calls for specific digital communication skills.
Emilio Ferreiro Lago, Sara Osuna Acedo
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Scale-Up Considerations of the Sundial Rotating Fresnel Solar Collector

SolarPACES Conference Proceedings
In the frame of the ASTEP project two prototypes of the Sundial collector, together with a Phase Change Material Thermal Energy Storage, will be tested integrated with the industrial processes of two sites.
Mercedes Ibarra, Rubén Barbero, Magdalena Barnetche, Rubén Abbas, Antonio Rovira   +4 more
doaj   +1 more source