Results 91 to 100 of about 1,047,569 (316)

The TRGB−SBF Project. III. Refining the HST Surface Brightness Fluctuation Distance Scale Calibration with JWST

open access: yesThe Astrophysical Journal
The TRGB−SBF Project team is developing an independent distance ladder using a geometrical calibration of the tip of the red giant branch (TRGB) method in elliptical galaxies that can, in turn, be used to set the surface brightness fluctuation (SBF ...
Joseph B. Jensen   +7 more
doaj   +1 more source

National culture dimension of power distance in the Baltic States

open access: yesJournal of Business Economics and Management, 2005
The paper presents a calculation for the values of power distance index in the countries of Latvia, Lithuania and Estonia using a mathematical model that is based on the correlations between power distance index values of the original research conducted ...
Stanislava Luptáková   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Gamma-Ray Bursts as Distance Indicators by a Statistical Learning Approach

open access: yesThe Astrophysical Journal Letters
Gamma-ray bursts (GRBs) can be probes of the early Universe, but currently, only 26% of GRBs observed by the Neil Gehrels Swift Observatory have known redshifts ( z ) due to observational limitations.
Maria Giovanna Dainotti   +8 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Period–Luminosity–Metallicity–Color Relations of Late-type Contact Binaries in the Big Data Era

open access: yesThe Astrophysical Journal
Binary stars ubiquitous throughout the Universe are important. Contact binaries (CBs) possessing period–luminosity (PL) relations could be adopted as distance tracers. The PL relations of CBs are influenced by metallicity abundance and color index, which
Lian-Yun Song, Zhi-Jia Tian
doaj   +1 more source

Measuring the Hubble Constant with the Hubble Space Telescope

open access: yes, 2009
Ten years ago our team completed the Hubble Space Telescope Key Project on the extragalactic distance scale. Cepheids were detected in some 25 galaxies and used to calibrate four secondary distance indicators that reach out into the expansion field ...
J. R. Mould   +6 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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