Results 101 to 110 of about 236,736 (305)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Period–Luminosity–Metallicity–Color Relations of Late-type Contact Binaries in the Big Data Era

open access: yesThe Astrophysical Journal
Binary stars ubiquitous throughout the Universe are important. Contact binaries (CBs) possessing period–luminosity (PL) relations could be adopted as distance tracers. The PL relations of CBs are influenced by metallicity abundance and color index, which
Lian-Yun Song, Zhi-Jia Tian
doaj   +1 more source

Linguistic Distances and Ethnolinguistic Fractionalization and Disenfranchisement Indices [PDF]

open access: yes, 2016
Ruhlen (1994) reconstructed 27 words of the very first language. Some linguists raised eyebrows about the words themselves, but not so much about the idea that all our languages descend from one, or a very small number of, language(s).1 Today, most linguists think that the diversity of languages is the result of the migration ‘out of Africa’ of Homo ...
Ginsburgh, Victor, Weber, Shlomo
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Near Miss Detection Using Distancing Monitoring and Distance-Based Proximal Indicators

open access: yesIEEE Access
Despite efforts to improve road safety, accidents persist due to insufficient evidence from manual police reporting, non-optimized detection algorithms, and technical limitations in real-time video processing and modelling.
Lek Ming Lim   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

On the Geography of Trade: Distance is Alive and Well [PDF]

open access: yes
It has been widely argued that, with the decline in trade costs, the importance of distance has declined over time. On the other hand, most gravity models find that the importance of distance has increased over time.
Céline CARRERE, Maurice SCHIFF
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Variables as stellar tracers and distance indicators [PDF]

open access: yes, 2015
The importance of pulsating stars as stellar population tracers and primary distance indicators is briefly reviewed. In particular, we discuss several approaches based on the comparison between the predictions of nonlinear convective pulsation models and
MARCONI, Marcella
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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