Results 131 to 140 of about 4,651,873 (337)

Market Indicators, Bank Fragility, and Indirect Market Discipline [PDF]

We examine whether two commonly used indicators of bank fragility, the subordinated debt spread and KMV’s distance to default, yield signals in line with supervisors’ interests.
Giuseppe Vulpes, Reint Gropp, Vesala Jukka   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Dealing with Imprecision in Performance Evaluation Processes Using Indicators: A Fuzzy Distance-Based Approach

, 2015
This paper presents an approach for dealing with imprecision in performance evaluation analysis focused particularly on Public Policy but applicable to other fields.
Gálvez Ruiz, David, Pino Mejías, José Luis   +1 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The relationship between anthropometric indicators and walking distance in patients with chronic obstructive pulmonary disease

, 2015
Shu-Chuan Ho,1,* Min-Fang Hsu,2,3,* Han-Pin Kuo,4 Jiun-Yi Wang,2 Li-Fei Chen,4 Kang-Yun Lee,5,6 Hsiao-Chi Chuang11School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 2Department of Healthcare Administration, Asia ...
Ho SC, Chen LF, Hsu MF, Kuo HP, Lee KY, Wang JY, Chuang HC   +6 more
core  

The socio-economic impacts of long distance commuting (LDC) on source communities [PDF]

, 2013
Background: The current mining boom has brought considerable wealth throughout Australia, but the benefits are not distributed evenly. The majority of Australian mining activities are in remote locations where demand for labour usually exceeds local ...
Hoath, Aileen, Aileen Hoath, McKenzie, Fiona Haslam, Fiona Haslam-McKenzie   +3 more
core  

Carnegie Supernova Project: Fast-declining Type Ia Supernovae as Cosmological Distance Indicators

The Astrophysical Journal
In this paper, the suitability of fast-declining Type Ia supernovae (SNe Ia) as cosmological standard candles is examined utilizing a “Hubble Flow” sample of 43 of these objects observed by the Carnegie Supernova Project (CSP).
M. M. Phillips, Syed A. Uddin, Christopher R. Burns, Nicholas B. Suntzeff, C. Ashall, E. Baron, L. Galbany, P. Hoeflich, E. Y. Hsiao, Nidia Morrell, S. E. Persson, Maximilian Stritzinger, Carlos Contreras, Wendy L. Freedman, Kevin Krisciunas, S. Kumar, J. Lu, Anthony L. Piro, M. Shahbandeh   +18 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

QUALITY INDICATORS AND INTERMEDIATE PRODUCTS: A NON-PARAMETRIC APPROACH

In this paper we propose a methodology to measure the characteristics and composition of intermediate products using productivity indicators based on directional distance functions.
Zago, Angelo M.
core