Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Vertical Head Movements Influence Memory Performance for Words With Emotional Content
Frontiers in Psychology, 2019 Numerous studies have found an association between valence and the vertical dimension of space (good-up, bad-down). This association has also been linked to sensorimotor experiences (e.g., body movements).
Laura K. Globig +2 more
doaj +1 more source
Open educational resources in Europe: A triptych of actions to support participation in higher education [PDF]
, 2006 In contrast to the face-to-face learning of campus based universities and the focus on traditional students, distance teaching universities focus on a mix of distance learning, e-learning, open learning, virtual mobility, learning communities, and the ...
Kirschner, Paul +3 more
core
Unsupervised Learning for Understanding Student Achievement in a Distance Learning Setting [PDF]
, 2017 Many factors could affect the achievement of students in distance learning settings. Internal factors such as age, gender, previous education level and engagement in online learning activities can play an important role in obtaining successful learning ...
d'Aquin, Mathieu, Liu, Shuangyan
core +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Issues in equivalence: Information literacy and the distance student [PDF]
, 2008 Information Literacy is a recognised lifelong learning skill, and an expected graduate attribute. With the growth in distance provision of tertiary education it is important to acknowledge the barriers faced by distance students and the difficulties ...
Lamond, Heather M., White, Bruce
core +1 more source
Library resources, student success and the distance-learning university [PDF]
, 2018 Purpose - Research at the Open University Library Services has been investigating the relationshipbetween access to online library resources and student success to help to understand whether there is asimilar relationship at a distance-learning ...
Baker, Kirsty +2 more
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Online pedagogy as a challenge to the traditional distance education paradigm [PDF]
, 2001 This paper briefly discusses the educational context at The University of Southern Queensland (USQ), Australia where many courses are delivered solely online.
McDonald, Jacquelin, Reushle, Shirley
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source