Results 21 to 30 of about 2,368,406 (271)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Croatian Economic SurveyThe large-scale war between Russia and Ukraine has increased global oil prices, signaling a new era of macroeconomic shock management for both developed and developing countries.
Lukman O. Oyelami +2 more
doaj +1 more source
Digital Presence and Online Identity among Digital Scholars: A Thematic Analysis
Social Sciences, 2023 In today’s postdigital society, the public presence of academics on the Web and the consequent affirmation of a given identity or of a multidimensional identity imply a much more complex and multifaceted management of their image than when we were ...
António Quintas-Mendes, Ana Paiva
doaj +1 more source
Meeting the growing demand for engineers and their educators: the potential for open and distance learning [PDF]
, 2007 As with all teaching, open and distance approaches are successful only if based on good pedagogical design addressing the purpose, structure and pace of the material, hence engaging students and encouraging active learning.
Bissell, Chris, Endean, Mark
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Communicating learning: evaluating the learning experience of distance learning students [PDF]
, 2008 Drawing upon research into students’ perceptions of their learning experience as distance learners, this paper explores what works well and what doesn’t.
Clarke, Julie +2 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Open PraxisThis study offers a systematic and critical examination of the research trends, thematic patterns, and scholarly evolution of Open Praxis during the 2023–2024 publication period.
Aras Bozkurt +2 more
doaj +1 more source
Higher Learning Research Communications, 2015 Online education has been steadily growing during the last decade. This growth has mainly taken place in the non-laboratory science fields. This essay describes some of the best practices to increase and maintain student retention, increase student ...
Eddy van Hunnik
doaj +1 more source