Results 31 to 40 of about 8,110,942 (288)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Social aspects associated with modern distance learning programmes [PDF]

open access: yes
The repositioning of the distance learning as a mode of course delivery is largely backed up by the recent advancements in communication technologies.
Amaratunga, Dilanthi   +2 more
core   +3 more sources

Radio and Distance Learning in Pakistan [PDF]

open access: yesMedia Asia, 1987
Radio is a powerful communication vehicle in Pakistan able to reach 3/4 of urban and 2/3 of rural households. Until 1974 most radio broadcasts of the Pakistan Broadcasting Corporation a state monopoly were in the categories of music drama and features; news and current affairs; and religious broadcasts.
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Models for Open and Distance Learning: Globalisation, Education and Distance Education [PDF]

open access: yes, 2003
The purpose of this paper, prepared for the Commonwealth of Learning (COL), is to support an informed dialogue on international, regional, national and institutional policy on globalisation and education, by looking particularly at crossborder ...
Hawkridge, David
core   +1 more source

Digital Presence and Online Identity among Digital Scholars: A Thematic Analysis

open access: yesSocial Sciences, 2023
In today’s postdigital society, the public presence of academics on the Web and the consequent affirmation of a given identity or of a multidimensional identity imply a much more complex and multifaceted management of their image than when we were ...
António Quintas-Mendes, Ana Paiva
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Research in Open and Distance Learning

open access: yes, 2011
Prof. Abtar Kaur, Open University Malaysia in conversation with Prof. Roger Mills, COL Consultant at the Sixth Pan-Commonwealth Forum on Open Learning (PCF6), Kochi, India, November 2010. Video Series on Open and Distance Learning.
Kaur, Abtar, Mills, Roger
core   +1 more source

Online college laboratory courses: Can they be done and will they affect graduation and retention rates?

open access: yesHigher Learning Research Communications, 2015
Online education has been steadily growing during the last decade. This growth has mainly taken place in the non-laboratory science fields. This essay describes some of the best practices to increase and maintain student retention, increase student ...
Eddy van Hunnik
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy