Results 81 to 90 of about 10,408,415 (315)

Heterodyne range imaging as an alternative to photogrammetry [PDF]

, 2007
Solid-state full-field range imaging technology, capable of determining the distance to objects in a scene simultaneously for every pixel in an image, has recently achieved sub-millimeter distance measurement precision.
Carnegie, Dale A., Conroy, Richard M., Cree, Michael J., Dorrington, Adrian A., Payne, Andrew D.   +4 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Distance Measurement Methods for Improved Insider Threat Detection

Secur. Commun. Networks, 2018
Insider threats are a considerable problem within cyber security and it is often difficult to detect these threats using signature detection. Increasing machine learning can provide a solution, but these methods often fail to take into account changes of
O. Lo, W. Buchanan, Paul Griffiths, Richard Macfarlane   +3 more
semanticscholar   +1 more source

Heisenberg's uncertainty principle for simultaneous measurement of positive-operator-valued measures

, 2008
A limitation on simultaneous measurement of two arbitrary positive operator valued measures is discussed. In general, simultaneous measurement of two noncommutative observables is only approximately possible.
H. Araki, H. J. Landau, Hideki Imai, M. Krishna, P. Busch, R. F. Werner, Takayuki Miyadera   +6 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Absolute distance measurement system with micron-grade measurement uncertainty and 24 m range using frequency scanning interferometry with compensation of environmental vibration.

Optics Express, 2016
We establish a theoretical model of the Doppler effect in absolute distance measurements using frequency scanning interferometry (FSI) and propose a novel FSI absolute distance measurement system.
Cheng Lu, Guodong Liu, Bingguo Liu, Fengdong Chen, Y. Gan   +4 more
semanticscholar   +1 more source

The distance and luminosity probability distributions derived from parallax and flux with their measurement errors with application to the millisecond pulsar PSR J0218+4232

, 2016
We use a Bayesian approach to derive the distance probability distribution for one object from its parallax with measurement uncertainty for two spatial distribution priors, viz.
Cator, E., Igoshev, A. P., Verbunt, F.
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source