Results 71 to 80 of about 1,870,807 (288)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Methods in Ecology and EvolutionKnowledge of variation in population processes (e.g. population growth) across broad spatiotemporal scales is fundamental to population ecology and critical for conservation decision‐making. Count data from rigorous surveys (e.g.
Qing Zhao +6 more
doaj +1 more source
Ecosphere, 2016 Robust models of wildlife population size, spatial distribution, and habitat relationships are needed to more effectively monitor endangered species and prioritize habitat conservation efforts. Remotely sensed data such as airborne laser altimetry (LiDAR)
Steven E. Sesnie +5 more
doaj +1 more source
SAMPLING VARIANCES OF HETEROZYGOSITY AND GENETIC DISTANCE [PDF]
Genetics, 1974 ABSTRACT Mathematical formulae for the sampling variances of average heterozygosity and Nei's genetic distance are developed. These sampling variances are decomposed into their two components, i.e. the inter-locus and intra-locus variances. The relationship between the number of loci and the number of individuals per locus to be examined
M, Nei, A K, Roychoudhury
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Environment and Natural Resources JournalHornbills belong to the Bucerotidae Family, and almost all species within this family are vulnerable to extinction. This study examined the population density of four hornbill species in the eastern part of the rainforest of the Huai Kha Khaeng Wildlife ...
Thanapong Fueakong +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
OryxEstimating the population size of shy and elusive species is challenging but necessary to inform appropriate conservation actions for threatened or declining species. Using camera-trap surveys conducted during 2017–2021, we estimated and compared African
Candice B. Lewis +3 more
doaj +1 more source
Rejection of Schmidt et al.'s estimators for bear population size
Ecology and Evolution, 2019 Aerial distance sampling of bears to estimate population size has been used throughout many parts of Alaska. The distance sampling models are complex since they need to account for undetected bears and differences in detection probabilities.
Earl Becker, Aaron Christ
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source