Results 71 to 80 of about 516,133 (259)
Evolutionary Algorithms for Query Op-timization in Distributed Database Sys-tems: A review
Advances in Distributed Computing and Artificial Intelligence Journal, 2018 Evolutionary Algorithms are bio-inspired optimization problem-solving approaches that exploit principles of biological evolution. , such as natural selection and genetic inheritance.
Zulfiqar ALI +2 more
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Building replicated database systems using distributed shared memory
Vetor, 2010 Este artigo apresenta uma abordagem para a construção de sistemas de base de dados replicados utilizando memória compartilhada distribuída. A arquitetura dsmDB, a qual implementa tal proposta, é apresentada.
Nelson Duarte Filho, Fernando Pedone
doaj +4 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Query acceleration in distributed database systems
Revista Colombiana de Computación, 2001 The advent of telecommunication era and the constant development of hardware and network structures have encouraged the decentralization of data while increasing the needs to access information from different sites.
Ramzi A. Haraty, Roula C. Fany
doaj
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Research and Implementation of Distributed Database HBase Monitoring System
MATEC Web of Conferences, 2017 With the arrival of large data age, distributed database HBase becomes an important tool for storing data in massive data age. The normal operation of HBase database is an important guarantee to ensure the security of data storage.
Guo Lisi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Current Situation and Development Trend of Database Technology
Gong-kuang zidonghua, 2011 Six stages of database system design were introduced which includes requirements analysis stage, concept and structure design stage, logic structure design stage, physical structure design stage, implementation stage, and stage of operation and ...
ZHANG Jun, WU Shao-hui
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source