Results 81 to 90 of about 4,637,209 (304)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
DCAD: a dual clustering algorithm for distributed spatial databases [PDF]
, 2007 Jiaogen Zhou, Jihong Guan, Pingxiang Li
openalex +1 more source
Evolutionary Algorithms for Query Op-timization in Distributed Database Sys-tems: A review
Advances in Distributed Computing and Artificial Intelligence Journal, 2018 Evolutionary Algorithms are bio-inspired optimization problem-solving approaches that exploit principles of biological evolution. , such as natural selection and genetic inheritance.
Zulfiqar ALI +2 more
doaj +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Building replicated database systems using distributed shared memory
Vetor, 2010 Este artigo apresenta uma abordagem para a construção de sistemas de base de dados replicados utilizando memória compartilhada distribuída. A arquitetura dsmDB, a qual implementa tal proposta, é apresentada.
Nelson Duarte Filho, Fernando Pedone
doaj +4 more sources
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Query acceleration in distributed database systems
Revista Colombiana de Computación, 2001 The advent of telecommunication era and the constant development of hardware and network structures have encouraged the decentralization of data while increasing the needs to access information from different sites.
Ramzi A. Haraty, Roula C. Fany
doaj
FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source