Results 81 to 90 of about 2,018,156 (259)

Stabilizing effect of delay distribution for a class of second-order systems without instantaneous feedback [PDF]

, 2009
In many situations in physics, engineering and biology time delays arise naturally due to the time needed to transport information from one part of the system to another and/or to react to incoming information. When differential equations are used in the
Gabor Kiss, Bernd Krauskopf, Kiss, G, Krauskopf, B   +3 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Existence and Uniqueness of Solutions for Cohen–Grossberg BAM Neural Networks with Time-Varying Leakage, Neutral, Distributed, and Transmission Delays

Mathematics
This paper establishes a rigorous theoretical framework for analyzing the existence and uniqueness of solutions to Cohen–Grossberg bidirectional associative memory neural networks (CGBAMNNs) incorporating four distinct types of time-varying delays ...
Er-Yong Cong, Xian Zhang, Li Zhu
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Global exponential periodicity of a class of bidirectional associative memory networks with finite distributed delays

, 2005
In this paper, we study the periodic oscillatory behavior of a class of bidirectional associative memory (BAM) networks with finite distributed delays.
Li, C., Yang, X., Megson, G.M., Evans, D.J., Liao, X., Li, C. D., Megson, G. M., Yang, X. F., Liao, X. F., Evans, D. J.   +9 more
core   +1 more source

Global Dynamics for a Distributed Delay SVEIR Model for Measles Transmission with Imperfect Vaccination: A Threshold Analysis

Mathematics
Measles remains a significant public health threat despite widespread vaccination, with recent resurgences driven by vaccine hesitancy and coverage gaps.
Mohammed H. Alharbi, Ali Rashash Alzahrani   +1 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Robust H∞ control for a class of nonlinear stochastic systems with mixed time delay [PDF]

, 2007
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2007 Wiley-Blackwell LtdThis paper is concerned with the problem of robust H∞ control for a class of uncertain nonlinear Itô-type ...
Liu, Y, Zidong Wang, Liu, X, Wang, Z, Yurong Liu, Xiaohui Liu   +5 more
core   +1 more source

Stochastic Synchronization of Reaction-Diffusion Neural Networks under General Impulsive Controller with Mixed Delays

Abstract and Applied Analysis, 2012
This paper investigates drive-response synchronization of a class of reaction-diffusion neural networks with time-varying discrete and distributed delays via general impulsive control method.
Xinsong Yang, Chuangxia Huang, Zhichun Yang   +2 more
doaj   +1 more source