A curated structural dataset of peptide-protein complexes reveals biases in existing datasets and principles of peptide binding. [PDF]
Protein SciHamdani R, Delgado J, Serrano L.
europepmc +1 more source
COCH Expression in the Hair Follicle Microenvironment Is Associated With Cortical Disulfide Bonding and Tensile Resistance in Aging Hair. [PDF]
Exp DermatolJoo HW +10 more
europepmc +1 more source
Advanced Science, EarlyView.Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen +12 more
wiley +1 more source
Association of the children's dietary inflammatory index (c-DII) with thiol/disulfide homeostasis in pediatric glycogen storage disease: a cross-sectional exploratory study. [PDF]
Front NutrKumru Akin B +3 more
europepmc +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Research Progress of Disulfide Bond Based Tumor Microenvironment Targeted Drug Delivery System [PDF]
Weiran Ma,1,2 Xiaoying Wang,2 Dongqi Zhang,3 Xupeng Mu1 1Scientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, 130033, People’s Republic of China; 2Jilin University School of Pharmaceutical Sciences, Changchun, 130021 ...
Zhang D, Mu X, Wang X, Ma W
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Dispersion management in highly nonlinear, carbon disulfide filled holey fibres
We investigate dispersion control in holey fibres incorporating a highly nonlinear liquid. A liquid-core microstructured fibre with extremely high nonlinearity and flat dispersion at telecoms wavelengths is ...
Camerlingo, A. +3 more
core +1 more source
Automated Multienzyme Digestion Workflows for Confident Characterization of Challenging Posttranslational Modifications in Therapeutic Antibodies by LC-MS/MS. [PDF]
Rapid Commun Mass SpectromEskesen NS +10 more
europepmc +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
, 2013 Tobacco mosaic virus (TMV) is a classical viral nanoarchitecture that has been extensively employed as a promising template for the fabrication of novel nanomaterials and nanostructures.
Dai, GL(戴高乐) +4 more
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