Results 121 to 130 of about 98,325 (259)
Volume kinetics of lactated Ringer's solution in adult horses
Equine Veterinary Journal, EarlyView.Abstract Background Fluid therapy in horses is primarily empirical. Evidence‐based quantification of the disposition of intravenous (IV) crystalloids used in clinical practice could enhance the effectiveness of fluid therapy. Objectives To determine the pharmacokinetics (i.e., volume kinetics: VK) and associated haemodynamic effects of IV lactated ...
William W. Muir +3 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To assess whether glucagon‐like‐peptide‐1 receptor (GLP‐1R) agonists could serve as a novel prophylactic treatment for migraine in patients with obesity. Background Increased intracranial pressure (ICP) is speculated to play a role in migraine mechanisms, as chronic migraine and idiopathic intracranial hypertension without ...
Simone Braca +6 more
wiley +1 more source
Mechanisms of intrinsic osmolality and sodium detection by magnocellular neurosecretory neurons
Journal of Neuroendocrinology, EarlyView.Abstract The maintenance of extracellular fluid (ECF) osmolality and sodium concentration ([Na+]o) near optimal “set point” values sustains physiological functions and prevents pathological states such as hypo‐ and hypernatremia. The peptide hormones vasopressin (antidiuretic hormone) and oxytocin (a natriuretic hormone in rats) play key roles in this ...
Sandra Salgado‐Mozo +6 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei +10 more
wiley +1 more source
Journal of Education, Health and Sport, 2017 The results in this article demonstrate of the dosage of the nephroprotective activity of the newly 7,8-substituted of theophylline are shown: 7-n-methylbenzyl-8-n-bromobenzylidenhydrazinotheophylline (code name benofillin).
O. P. Matviychuk +3 more
doaj
Empagliflozin does not prevent progression of Dent's disease type 1 in a mouse model
Experimental Physiology, EarlyView.Abstract Dent's disease is a rare inherited renal disorder characterized by generalized proximal tubule dysfunction with low molecular weight proteinuria, hypercalciuria, and urinary loss of other solutes. The disease is progressive and leads to chronic kidney disease.
Elise de Combiens +6 more
wiley +1 more source
Circulation: Heart FailureBackground: The use of urinary sodium to guide diuretics in acute heart failure is recommended by experts and the most recent European Society of Cardiology guidelines. However, there are limited data to support this recommendation.
Jeroen Dauw +33 more
semanticscholar +1 more source
Experimental Physiology, EarlyView.Abstract Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla +9 more
wiley +1 more source